Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 6/20 | 0.71 |
| ▸ | MAPT | P10636 | 6/20 | 0.71 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.71 |
| ▸ | HPGD | P15428 | 2/20 | 0.71 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.71 |
| ▸ | MEN1 | O00255 | 5/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | NPY1R | P25929 | 1/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.45 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9871524 | 0.82 | LMNA (0.52) | LMNAMAPTALDH1A1HPGDALOX12 | |
| SCHEMBL20496880 | 0.79 | ALDH1A1 (0.56) | LMNAMAPTALDH1A1HPGDALOX12 | |
| Dimethylamine SCHEMBL9871083 | 0.77 | ALDH1A1 (0.55) | LMNAMAPTALDH1A1HPGDALOX12 | |
| Dimethylamine SCHEMBL9872444 | 0.75 | TAAR1 (0.53) | LMNAMAPTALDH1A1HPGDALOX12 | |
| SCHEMBL15033625 | 0.75 | LMNA (0.74) | LMNAMAPTALDH1A1HPGDALOX12 | |
| SCHEMBL15033633 | 0.75 | LMNA (0.62) | LMNAMAPTALDH1A1HPGDALOX12 | |
| SCHEMBL15033615 | 0.74 | LMNA (0.61) | LMNAMAPTALDH1A1HPGDALOX12 | |
| SCHEMBL15033620 | 0.73 | LMNA (0.60) | LMNAMAPTALDH1A1HPGDALOX12 | |
| SCHEMBL15033618 | 0.73 | LMNA (0.60) | LMNAMAPTALDH1A1HPGDALOX12 | |
| SCHEMBL15022960 | 0.73 | LMNA (0.60) | LMNAMAPTALDH1A1HPGDALOX12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5021429-A | Histamine h2-antagonists; antisecretory-antiallergen agent; skin disorders and peptic ulcers | ALLEN & HANSBURYS LIMITED (GB) | 1991-06-04 | — | — | US | disclosed |