Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRL1 | P41146 | 4/20 | 0.49 |
| ▸ | CCR3 | P51677 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 3/20 | 0.48 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.47 |
| ▸ | OPRK1 | P41145 | 3/20 | 0.47 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | TACR1 | P25103 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | HTR2C | P28335 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3898508 | 0.78 | OPRL1 (0.79) | OPRL1CCR3POLBOPRM1OPRK1 | |
| SCHEMBL22004727 | 0.73 | L3MBTL1 (0.53) | POLBMEN1KMT2AL3MBTL1 | |
| SCHEMBL7446018 | 0.72 | L3MBTL1 (0.49) | OPRL1POLBOPRM1MEN1KMT2A | |
| SCHEMBL3235714 | 0.72 | OPRL1 (0.79) | OPRL1CCR3POLBOPRM1OPRK1 | |
| SCHEMBL7436778 | 0.71 | L3MBTL1 (0.48) | OPRL1POLBOPRM1MEN1KMT2A | |
| SCHEMBL7443185 | 0.71 | L3MBTL1 (0.48) | OPRL1POLBOPRM1MEN1KMT2A | |
| SCHEMBL8751541 | 0.71 | KDM4E (0.56) | OPRL1CCR3POLBOPRM1OPRK1 | |
| SCHEMBL7436417 | 0.69 | L3MBTL1 (0.46) | OPRL1POLBOPRM1OPRK1MEN1 | |
| SCHEMBL18204153 | 0.69 | CYP2D6 (0.50) | POLBMEN1KMT2AL3MBTL1 | |
| SCHEMBL23132436 | 0.68 | L3MBTL1 (0.39) | MEN1KMT2AL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5021420-A | Antiserotonine agents; central nervous system, gastroin-testinal and cardiovascular disorders | RHONE-POULENC SANTE (FR) | 1991-06-04 | — | — | US | disclosed |