Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNA5 | P22460 | 6/20 | 0.37 |
| ▸ | PTGDR2 | Q9Y5Y4 | 3/20 | 0.37 |
| ▸ | CXCR3 | P49682 | 2/20 | 0.35 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | PTGER2 | P43116 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA4 | P22748 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | RORC | P51449 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12948710 | 0.88 | KCNA5 (0.37) | KCNA5PTGDR2CXCR3PTGER1KMT2A | |
| SCHEMBL988942 | 0.85 | PTGDR2 (0.42) | KCNA5PTGDR2PTGER1ALDH1A1LMNA | |
| SCHEMBL987918 | 0.81 | PTGDR2 (0.50) | KCNA5PTGDR2CXCR3PTGER1KMT2A | |
| SCHEMBL1082349 | 0.81 | MLNR (0.40) | KCNA5PTGDR2CXCR3KMT2AALDH1A1 | |
| SCHEMBL988505 | 0.79 | PTGDR2 (0.52) | KCNA5PTGDR2CXCR3PTGER1KMT2A | |
| SCHEMBL988484 | 0.78 | PTGDR2 (0.43) | PTGDR2PTGER1ALDH1A1LMNARORC | |
| SCHEMBL987937 | 0.78 | PTGDR2 (0.43) | PTGDR2ALDH1A1LMNA | |
| SCHEMBL14885448 | 0.78 | PTGDR2 (0.42) | PTGDR2PTGER1PTGER2ALDH1A1LMNA | |
| SCHEMBL2772080 | 0.77 | MAOA (0.35) | PTGDR2PTGER1KMT2AALDH1A1LMNA | |
| SCHEMBL987762 | 0.75 | PTGDR2 (0.55) | PTGDR2PTGER1PTGER2ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011002814-A2 | BIARYL OXYACETIC ACID COMPOUNDS | LIGAND PHARMACEUTICALS INC. (US) | 2011-01-06 | — | — | WO | disclosed |