Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.58 |
| ▸ | NPC1 | O15118 | 3/20 | 0.58 |
| ▸ | RAB9A | P51151 | 3/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.58 |
| ▸ | POLB | P06746 | 7/20 | 0.57 |
| ▸ | GAA | P10253 | 1/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.54 |
| ▸ | HPGD | P15428 | 2/20 | 0.54 |
| ▸ | TP53 | P04637 | 1/20 | 0.54 |
| ▸ | BLM | P54132 | 1/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.53 |
| ▸ | PKM | P14618 | 1/20 | 0.53 |
| ▸ | APEX1 | P27695 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9870116 | 0.80 | MAPT (0.63) | MAPTSMN1; SMN2NPC1RAB9AL3MBTL1 | |
| SCHEMBL2485359 | 0.79 | RAB9A (0.75) | MAPTSMN1; SMN2NPC1RAB9APOLB | |
| SCHEMBL15818387 | 0.78 | PRMT5 (0.69) | MAPTSMN1; SMN2NPC1RAB9AL3MBTL1 | |
| SCHEMBL9871951 | 0.78 | MAPT (0.60) | MAPTSMN1; SMN2NPC1RAB9AL3MBTL1 | |
| SCHEMBL1101354 | 0.77 | RAB9A (0.60) | MAPTSMN1; SMN2NPC1RAB9APOLB | |
| SCHEMBL3453971 | 0.77 | KDM4E (0.64) | MAPTSMN1; SMN2NPC1RAB9APOLB | |
| SCHEMBL28678208 | 0.77 | MAPT (1.00) | MAPTSMN1; SMN2NPC1RAB9AL3MBTL1 | |
| SCHEMBL9871210 | 0.77 | RAB9A (0.69) | MAPTSMN1; SMN2NPC1RAB9AL3MBTL1 | |
| SCHEMBL19171440 | 0.76 | PRMT5 (0.67) | MAPTSMN1; SMN2NPC1RAB9AL3MBTL1 | |
| SCHEMBL30345053 | 0.76 | KDM4E (0.59) | MAPTSMN1; SMN2NPC1RAB9AL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5023333-A | Derivatives of 8-hydroxyquinoline | CIBA-GEIGY CORPORATION (US) | 1991-06-11 | — | — | US | claimed |