Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.45 |
| ▸ | MEN1 | O00255 | 5/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.40 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.40 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.40 |
| ▸ | PHGDH | O43175 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6744475 | 0.81 | SIGMAR1 (0.54) | ALDH1A1TDP1KMT2AMEN1LMNA | |
| SCHEMBL5963434 | 0.73 | L3MBTL1 (0.49) | ALDH1A1KMT2AMEN1SIGMAR1CYP2D6 | |
| SCHEMBL28946773 | 0.70 | POLB (0.50) | ALDH1A1KMT2AMEN1LMNASIGMAR1 | |
| SCHEMBL28659205 | 0.70 | SIGMAR1 (0.50) | TDP1KMT2AMEN1LMNAHTT | |
| SCHEMBL1520110 | 0.69 | SIGMAR1 (0.45) | ALDH1A1TDP1KMT2AMEN1LMNA | |
| SCHEMBL9726041 | 0.69 | MC4R (0.47) | ALDH1A1KMT2AMEN1LMNAHTT | |
| SCHEMBL10199565 | 0.68 | L3MBTL1 (0.59) | ALDH1A1KMT2AMEN1CYP2D6CYP2C9 | |
| SCHEMBL16786536 | 0.67 | SIGMAR1 (0.58) | KMT2AMEN1LMNASIGMAR1CYP2D6 | |
| SCHEMBL12334054 | 0.67 | CYP2D6 (0.46) | ALDH1A1TDP1KMT2AMEN1LMNA | |
| SCHEMBL2678678 | 0.67 | SIGMAR1 (0.58) | ALDH1A1TDP1LMNASIGMAR1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5019611-A | Tetrahydrotriazinethiones | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1991-05-28 | — | — | US | disclosed |
| EP-0278890-A2 | Non-staining and slightly-staining antiozonants | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1988-08-17 | — | — | EP | disclosed |