Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PHGDH | O43175 | 2/20 | 0.68 |
| ▸ | MGLL | Q99685 | 3/20 | 0.52 |
| ▸ | FAAH | O00519 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | ADH1C | P00326 | 2/20 | 0.33 |
| ▸ | ADH1A | P07327 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.31 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.31 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.31 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8468236 | 0.81 | PHGDH (1.00) | PHGDHMGLLFAAHALDH1A1HTT | |
| SCHEMBL11569028 | 0.78 | PHGDH (0.63) | PHGDHMGLLFAAHALDH1A1ADH1C | |
| SCHEMBL11591673 | 0.77 | PHGDH (0.68) | PHGDHMGLLFAAHALDH1A1LMNA | |
| SCHEMBL1001644 | 0.73 | PHGDH (0.62) | PHGDHMGLLFAAHALDH1A1HTT | |
| SCHEMBL6830758 | 0.72 | PHGDH (0.80) | PHGDHMGLLFAAHALDH1A1 | |
| SCHEMBL9871394 | 0.72 | PHGDH (0.61) | PHGDHMGLLFAAHALDH1A1ADH1C | |
| SCHEMBL1426473 | 0.72 | PHGDH (0.61) | PHGDHMGLLFAAHALDH1A1ADH1C | |
| SCHEMBL27590680 | 0.71 | PHGDH (0.60) | PHGDHMGLLFAAHALDH1A1ADH1C | |
| SCHEMBL27326575 | 0.71 | PHGDH (0.60) | PHGDHMGLLFAAHALDH1A1ADH1C | |
| SCHEMBL3072501 | 0.70 | PHGDH (0.58) | PHGDHMGLLFAAHALDH1A1ADH1C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5019611-A | Tetrahydrotriazinethiones | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1991-05-28 | — | — | US | disclosed |
| EP-0278890-A2 | Non-staining and slightly-staining antiozonants | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1988-08-17 | — | — | EP | disclosed |