Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.34 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | PTAFR | P25105 | 1/20 | 0.32 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.32 |
| ▸ | P2RX2 | Q9UBL9 | 1/20 | 0.32 |
| ▸ | ALPL | P05186 | 3/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | CA9 | Q16790 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7046102 | 0.84 | ALDH1A1 (0.39) | SMN1; SMN2PKMTRPV4TSHRALDH1A1 | |
| SCHEMBL592705 | 0.73 | CYP3A4 (0.39) | SMN1; SMN2TSHRALDH1A1KDM4ECA12 | |
| SCHEMBL8126924 | 0.73 | ALDH1A1 (0.53) | ALDH1A1GAAPOLBMAPK1LMNA | |
| SCHEMBL1374507 | 0.73 | ALDH1A1 (0.39) | SMN1; SMN2PKMTRPV4TSHRALDH1A1 | |
| SCHEMBL1637863 | 0.70 | ACHE (0.39) | KDM4ECA9CYP19A1 | |
| SCHEMBL7684229 | 0.69 | TAAR1 (0.44) | TSHRALDH1A1GAAMAPK1KDM4E | |
| SCHEMBL1423798 | 0.69 | EGFR (0.31) | SMN1; SMN2PKM | |
| SCHEMBL1096159 | 0.69 | SMN1; SMN2 (0.47) | SMN1; SMN2PKMTRPV4TSHRGAA | |
| SCHEMBL9166696 | 0.68 | TUBB1 (0.38) | ALDH1A1GAAPOLBKDM4E | |
| SCHEMBL7255898 | 0.68 | ACHE (0.33) | ALDH1A1MAPK1LMNACA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5049560-A | Anticoagulants, platelet activating factor | SOCIETE DE CONSEILS DE RECHERCHES ET D'APPLICATIONS SCIENTIFIQUES (S.C.R.A.S.) (FR) | 1991-09-17 | — | — | US | disclosed |