Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | BLM | P54132 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | TRIM24 | O15164 | 2/20 | 0.35 |
| ▸ | TRIM33 | Q9UPN9 | 2/20 | 0.35 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.34 |
| ▸ | LY96 | Q9Y6Y9 | 1/20 | 0.33 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.33 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.33 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3905460 | 0.97 | LMNA (0.40) | LMNAMEN1THRBBLMKMT2A | |
| Ethylene Glycol SCHEMBL5734322 | 0.94 | LMNA (0.35) | LMNAMEN1THRBBLMKMT2A | |
| Ortho-Phthalaldehyde SCHEMBL2474511 | 0.85 | LMNA (0.52) | LMNAMEN1THRBBLMKMT2A | |
| Ethylene SCHEMBL8376511 | 0.83 | LMNA (0.42) | LMNAMEN1THRBBLMKMT2A | |
| Ethylene SCHEMBL7471800 | 0.81 | LMNA (0.38) | LMNAMEN1THRBBLMKMT2A | |
| Ethylene SCHEMBL3874360 | 0.79 | LMNA (0.57) | LMNAMEN1THRBBLMKMT2A | |
| SCHEMBL6324 | 0.78 | LMNA (0.43) | LMNAMEN1THRBBLMKMT2A | |
| 2-Chloronicotinaldehyde SCHEMBL9542660 | 0.78 | TRIM24 (0.39) | LMNAALDH1A1GAAHPGDHTT | |
| SCHEMBL11323911 | 0.78 | LMNA (0.40) | LMNAMEN1THRBBLMKMT2A | |
| Salicyladehyde SCHEMBL6903346 | 0.78 | TRIM24 (0.60) | LMNAMEN1THRBBLMKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4988707-A | Platelet activating factor, antiinflammatory agents, cardiovascular disorders and treatment of asthma | G. D. SEARLE & CO. (US) | 1991-01-29 | — | — | US | disclosed |