Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | METAP1 | P53582 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
| ▸ | MPO | P05164 | 5/20 | 0.34 |
| ▸ | HAVCR2 | Q8TDQ0 | 1/20 | 0.34 |
| ▸ | XDH | P47989 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | HTR6 | P50406 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | KRAS | P01116 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7408263 | 0.75 | KMT2A (0.43) | METAP1KMT2AALDH1A1HTR6KDM4E | |
| SCHEMBL9872549 | 0.74 | CYP3A4 (0.51) | KMT2AMEN1CYP3A4MAPTALDH1A1 | |
| Hydrochloric Acid SCHEMBL7433749 | 0.72 | HTR6 (0.51) | METAP1KMT2AALDH1A1HTR6KDM4E | |
| Hydrochloric Acid SCHEMBL9872665 | 0.72 | HTR2C (0.34) | HTR2C | |
| SCHEMBL11384705 | 0.71 | HTR6 (0.39) | KMT2AMEN1CYP3A4MAPTSLC6A4 | |
| SCHEMBL9871149 | 0.71 | CYP3A4 (0.38) | METAP1KMT2AMEN1CYP3A4ALDH1A1 | |
| Hydrochloric Acid SCHEMBL9872164 | 0.70 | METAP1 (0.39) | METAP1CYP3A4ALDH1A1HTR6CYP1A2 | |
| SCHEMBL7605648 | 0.68 | METAP1 (0.56) | METAP1MAPTALDH1A1HPGD | |
| Hydrochloric Acid SCHEMBL10916080 | 0.67 | METAP1 (0.57) | METAP1MAPTALDH1A1HPGD | |
| SCHEMBL10395714 | 0.66 | MAPT (0.37) | METAP1KMT2AMEN1CYP3A4MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5030646-A | Treatment of diseases resulting from disfunction of seretoninergic system | ADIR ET COMPAGNIE (FR) | 1991-07-09 | — | — | US | disclosed |