Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.57 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.46 |
| ▸ | PSEN1 | P49768 | 3/20 | 0.44 |
| ▸ | PSEN2 | P49810 | 3/20 | 0.44 |
| ▸ | APH1B | Q8WW43 | 3/20 | 0.44 |
| ▸ | NCSTN | Q92542 | 3/20 | 0.44 |
| ▸ | APH1A | Q96BI3 | 3/20 | 0.44 |
| ▸ | PSENEN | Q9NZ42 | 3/20 | 0.44 |
| ▸ | CA1 | P00915 | 2/20 | 0.44 |
| ▸ | CA4 | P22748 | 2/20 | 0.44 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.44 |
| ▸ | CA3 | P07451 | 1/20 | 0.44 |
| ▸ | CDC25B | P30305 | 1/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | CA5A | P35218 | 1/20 | 0.43 |
| ▸ | CA7 | P43166 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10439532 | 1.00 | LMNA (0.57) | LMNAPTPN1PSEN1PSEN2APH1B | |
| SCHEMBL7081405 | 0.78 | CYP3A4 (0.54) | LMNACA1CA4CA14CA3 | |
| SCHEMBL3142790 | 0.78 | LMNA (0.63) | LMNAPTPN1CDC25BHTTMAPT | |
| SCHEMBL11372268 | 0.76 | LMNA (0.50) | LMNAPTPN1CDC25BHTTL3MBTL1 | |
| SCHEMBL8935305 | 0.75 | PTPN1 (0.57) | LMNAPTPN1CDC25BL3MBTL1TSHR | |
| SCHEMBL8935309 | 0.75 | PTPN1 (0.57) | LMNAPTPN1CDC25BL3MBTL1TSHR | |
| SCHEMBL10280608 | 0.75 | PSEN1 (0.54) | LMNAPSEN1PSEN2APH1BNCSTN | |
| SCHEMBL6336780 | 0.75 | LMNA (0.49) | LMNAPTPN1CDC25BHTTL3MBTL1 | |
| SCHEMBL8308521 | 0.74 | LMNA (0.58) | LMNAPTPN1CDC25BL3MBTL1TSHR | |
| SCHEMBL883429 | 0.74 | LMNA (0.58) | LMNAPTPN1CDC25BL3MBTL1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4985571-A | 6-membered lactones useful as intermediates for antilipemic mevalonic acid lactones | Takano, Seiichi (JP) | 1991-01-15 | — | — | US | disclosed |