Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 2/20 | 0.57 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | CDC25B | P30305 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | AKT1 | P31749 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | DRD1 | P21728 | 1/20 | 0.39 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | HRH4 | Q9H3N8 | 4/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8935309 | 1.00 | PTPN1 (0.57) | PTPN1LMNACDC25BCYP3A4AKT1 | |
| SCHEMBL9269173 | 0.83 | LMNA (0.53) | PTPN1LMNACDC25BCYP3A4AKT1 | |
| SCHEMBL3142790 | 0.81 | LMNA (0.63) | PTPN1LMNACDC25BAKT1L3MBTL1 | |
| SCHEMBL10439532 | 0.75 | LMNA (0.57) | PTPN1LMNACDC25BAKT1L3MBTL1 | |
| SCHEMBL9872188 | 0.75 | LMNA (0.57) | PTPN1LMNACDC25BAKT1L3MBTL1 | |
| SCHEMBL8980491 | 0.74 | LMNA (0.56) | PTPN1LMNACDC25BAKT1L3MBTL1 | |
| SCHEMBL22569916 | 0.74 | LMNA (0.56) | PTPN1LMNACDC25BCYP3A4AKT1 | |
| SCHEMBL15084444 | 0.74 | LMNA (0.56) | PTPN1LMNACDC25BCYP3A4AKT1 | |
| SCHEMBL3143177 | 0.74 | LMNA (0.55) | PTPN1LMNACDC25BAKT1L3MBTL1 | |
| SCHEMBL6282511 | 0.73 | LMNA (0.55) | PTPN1LMNACDC25BAKT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-4049287-A | — | — | None | — | — | JP | disclosed |
| US-5504219-A | Optically active compounds and intermediates thereof, and process for manufacturing same | ASAHI DENKA KOGYO K.K. (JP) | 1996-04-02 | — | — | US | disclosed |
| US-5352845-A | Process for manufacture of optically active saturated compounds | ASAHI DENKA KOGYO K.K. (JP) | 1994-10-04 | — | — | US | disclosed |
| US-5262552-A | Optically active compounds and intermediates thereof, and process for manufacturing same | ASAHI DENKA KOGYO K.K. (JP) | 1993-11-16 | — | — | US | disclosed |
| JP-H0449287-A | OPTICALLY ACTIVE DELTA-LACTONE DERIVATIVE | ASAHI DENKA KOGYO KK | 1992-02-18 | — | — | JP | disclosed |