Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.42 |
| ▸ | DPP4 | P27487 | 3/20 | 0.41 |
| ▸ | DPP8 | Q6V1X1 | 2/20 | 0.41 |
| ▸ | DPP9 | Q86TI2 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | CREBBP | Q92793 | 2/20 | 0.35 |
| ▸ | FABP3 | P05413 | 1/20 | 0.33 |
| ▸ | FABP4 | P15090 | 1/20 | 0.33 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.33 |
| ▸ | DHODH | Q02127 | 2/20 | 0.33 |
| ▸ | EP300 | Q09472 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.33 |
| ▸ | GCGR | P47871 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9879298 | 0.91 | ADORA3 (0.41) | ADORA3MEN1KMT2AL3MBTL1CREBBP | |
| SCHEMBL9265733 | 0.76 | GCGR (0.50) | MEN1KMT2AL3MBTL1ALDH1A1GCGR | |
| SCHEMBL8114161 | 0.75 | KDM4E (0.36) | MEN1KMT2ACREBBPEP300ALDH1A1 | |
| SCHEMBL9872670 | 0.75 | ADORA3 (0.32) | ADORA3MEN1KMT2AALDH1A1 | |
| SCHEMBL9872661 | 0.75 | HMGCR (0.35) | ADORA3MEN1KMT2ACREBBPALDH1A1 | |
| SCHEMBL9870568 | 0.74 | DPP4 (0.50) | DPP4DPP8DPP9FABP3FABP4 | |
| SCHEMBL27525559 | 0.74 | PRKAA2 (0.51) | DPP4DPP8DPP9FABP3FABP4 | |
| SCHEMBL6958480 | 0.72 | GCGR (0.61) | GCGR | |
| SCHEMBL6949644 | 0.71 | GCGR (0.41) | GCGR | |
| SCHEMBL2647574 | 0.71 | PRKAA2 (0.47) | DPP4DPP8DPP9FABP4FABP5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4997837-A | Enzyme inhibitors | WARNER-LAMBERT COMPANY (US) | 1991-03-05 | — | — | US | disclosed |
| US-4906624-A | 6-(((Substituted)pyridin-3-yl)alkyl)-and alkenyl)-tetrahydro-4-hydroxypyran-2-one inhibitors of cholesterol biosynthesis | WARNER-LAMBERT COMPANY (US) | 1990-03-06 | — | — | US | disclosed |
| EP-0306929-A2 | 6-[[(Substituted)pyridin-3-YL]alkyl]-and alkenyl]-tetrahydro-4-hydroxypyran-2-one inhibitors of cholesterol biosynthesis | WARNER-LAMBERT COMPANY (US) | 1989-03-15 | — | — | EP | disclosed |