Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA1D | Q01668 | 14/20 | 1.00 |
| ▸ | ADORA3 | P0DMS8 | 5/20 | 0.57 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.52 |
| ▸ | CACNA1S | Q13698 | 1/20 | 0.52 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.52 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9873467 | 0.89 | CACNA1D (0.80) | CACNA1DADORA3CACNA1FCACNA1SCACNA1C | |
| SCHEMBL9875091 | 0.80 | CACNA1D (0.72) | CACNA1DADORA3CACNA1FCACNA1SCACNA1C | |
| SCHEMBL11798629 | 0.79 | CACNA1D (0.65) | CACNA1DADORA3CACNA1FCACNA1SCACNA1C | |
| SCHEMBL3027749 | 0.77 | ADORA3 (0.90) | CACNA1DADORA3CACNA1FCACNA1SCACNA1C | |
| SCHEMBL11802006 | 0.76 | CACNA1D (0.77) | CACNA1DADORA3 | |
| SCHEMBL9433876 | 0.74 | CACNA1D (0.58) | CACNA1DADORA3CACNA1FCACNA1SCACNA1C | |
| SCHEMBL11008647 | 0.74 | CACNA1C (0.72) | CACNA1DADORA3CACNA1FCACNA1SCACNA1C | |
| SCHEMBL7159073 | 0.73 | ADORA3 (1.00) | CACNA1DADORA3CACNA1FCACNA1SCACNA1C | |
| SCHEMBL19752618 | 0.72 | CA12 (0.68) | ADORA3 | |
| SCHEMBL5339709 | 0.72 | CA12 (0.68) | ADORA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4990507-A | Cardiotonic agents | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1991-02-05 | — | — | US | disclosed |
| EP-0228845-B1 | N-CONTAINING HETEROCYCLIC COMPOUNDS, PROCESSES FOR THE PREPARATION THEREOF AND COMPOSITION COMPRISING THE SAME | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1990-12-12 | — | — | EP | disclosed |
| US-4931453-A | CARDIOVASCULAR, HYPOTENSIVE AGENTS | FUJISAWA PHARMACEUTICAL COMPANY, LTD. (JP) | 1990-06-05 | — | — | US | disclosed |
| US-4857527-A | HYPOTENSIVE, ANTISCHEMIC AGENT | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1989-08-15 | — | — | US | disclosed |
| US-4831030-A | FOR CEREBROVASCULAR DISEASES; HYPERTENSIVE AGENTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1989-05-16 | — | — | US | disclosed |
| EP-0228845-A2 | N-containing heterocyclic compounds, processes for the preparation thereof and composition comprising the same | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1987-07-15 | — | — | EP | disclosed |