SCHEMBL9872376

SCHEMBL9872376

O=C(CCC(=S)c1cc(N2C(=O)C3=C(CCCC3)C2=O)c(F)cc1Cl)N1CCCCC1

nearest known ligand 0.53

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
HPGD P15428 1/20 0.42
GRM7 Q14831 1/20 0.38
GRM4 Q14833 1/20 0.38
MAPT P10636 1/20 0.37
KMT2A Q03164 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9873912 0.99 HPGD (0.40) HPGDGRM7GRM4MAPTKMT2A
SCHEMBL9871727 0.84 GRM7 (0.40) GRM7GRM4
SCHEMBL9872371 0.81 HPGD (0.41) HPGDGRM7GRM4
SCHEMBL9870902 0.80 GRM7 (0.40) GRM7GRM4
SCHEMBL10529972 0.80 GRM7 (0.40) GRM7GRM4
SCHEMBL9872381 0.78 HPGD (0.45) HPGDMAPTKMT2A
SCHEMBL9871821 0.78 GRM7 (0.43) GRM7GRM4
SCHEMBL9765563 0.76 GRM7 (0.47) GRM7GRM4
SCHEMBL29077296 0.76 GRM7 (0.47) GRM7GRM4
SCHEMBL9873270 0.76 PPOX (0.40) GRM7GRM4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5007951-A Pre- or postemergent herbicides for use with crops CIBA-GEIGY CORPORATION (US) 1991-04-16 US disclosed