Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.52 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.52 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 3/20 | 0.51 |
| ▸ | NPC1 | O15118 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.49 |
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.48 |
| ▸ | CHRNA5 | P30532 | 1/20 | 0.48 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.48 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | F2 | P00734 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9873005 | 0.81 | TDP1 (0.53) | TDP1KMT2AMAPK1HIF1ASLC6A2 | |
| SCHEMBL2452177 | 0.77 | PPM1B (0.51) | TDP1KMT2AMAPK1HIF1ASLC6A2 | |
| SCHEMBL2452175 | 0.77 | PPM1B (0.51) | TDP1KMT2AMAPK1HIF1ASLC6A2 | |
| SCHEMBL9172397 | 0.77 | PPM1B (0.51) | TDP1KMT2AMAPK1HIF1ASLC6A2 | |
| SCHEMBL9872467 | 0.76 | TDP1 (0.47) | TDP1KMT2AMAPK1HIF1ASLC6A2 | |
| SCHEMBL8447322 | 0.76 | CARM1 (0.61) | TDP1KMT2AMAPK1HIF1ASLC6A2 | |
| SCHEMBL532785 | 0.76 | CARM1 (0.61) | TDP1KMT2AMAPK1HIF1ASLC6A2 | |
| SCHEMBL13286850 | 0.76 | PPM1B (0.56) | TDP1KMT2AMAPK1HIF1ASLC6A2 | |
| SCHEMBL28655049 | 0.74 | TDP1 (0.53) | TDP1KMT2AMAPK1HIF1ASLC6A2 | |
| SCHEMBL7700089 | 0.74 | TDP1 (0.53) | TDP1KMT2AMAPK1HIF1ASLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4988703-A | Viricides of hydroxyethylcyclopropylguanine | ABBOTT LABORATORIES (US) | 1991-01-29 | — | — | US | disclosed |