Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.46 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.43 |
| ▸ | CHRNA5 | P30532 | 1/20 | 0.43 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.43 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | F2 | P00734 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9873005 | 0.80 | TDP1 (0.53) | TDP1MAPK1HIF1ASLC6A2SLC6A3 | |
| SCHEMBL15468161 | 0.77 | ALDH1A1 (0.43) | TDP1MAPK1HIF1ASLC6A2SLC6A3 | |
| SCHEMBL9872465 | 0.76 | TDP1 (0.53) | TDP1MAPK1HIF1ASLC6A2SLC6A3 | |
| SCHEMBL2452177 | 0.72 | PPM1B (0.51) | TDP1MAPK1HIF1ASLC6A2SLC6A3 | |
| SCHEMBL9172397 | 0.72 | PPM1B (0.51) | TDP1MAPK1HIF1ASLC6A2SLC6A3 | |
| SCHEMBL2452175 | 0.72 | PPM1B (0.51) | TDP1MAPK1HIF1ASLC6A2SLC6A3 | |
| SCHEMBL14397614 | 0.72 | CARM1 (0.52) | TDP1MAPK1HIF1ASLC6A2SLC6A3 | |
| SCHEMBL8050038 | 0.71 | CARM1 (0.48) | TDP1MAPK1HIF1ASLC6A2SLC6A3 | |
| SCHEMBL21783220 | 0.71 | LGALS9 (0.44) | TDP1MAPK1HIF1ASLC6A2SLC6A3 | |
| SCHEMBL8447322 | 0.70 | CARM1 (0.61) | TDP1MAPK1HIF1ASLC6A2SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4988703-A | Viricides of hydroxyethylcyclopropylguanine | ABBOTT LABORATORIES (US) | 1991-01-29 | — | — | US | disclosed |