SCHEMBL987247

SCHEMBL987247

COc1cccnc1-c1ccccc1

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SYK P43405 2/20 0.51
AURKB Q96GD4 2/20 0.51
INCENP Q9NQS7 2/20 0.51
KDM4E B2RXH2 3/20 0.50
ALDH1A1 P00352 2/20 0.50
LMNA P02545 2/20 0.50
GAA P10253 1/20 0.50
CYP11B1 P15538 2/20 0.49
CYP11B2 P19099 2/20 0.49
HPGD P15428 1/20 0.47
KDR P35968 1/20 0.47
SMN1; SMN2 Q16637 1/20 0.46
CA12 O43570 1/20 0.46
CA1 P00915 1/20 0.46
CA2 P00918 1/20 0.46
CA4 P22748 1/20 0.46
CA7 P43166 1/20 0.46
CA9 Q16790 1/20 0.46
CA14 Q9ULX7 1/20 0.46
L3MBTL1 Q9Y468 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4056517 0.96 SYK (0.53) SYKAURKBINCENPKDM4EALDH1A1
SCHEMBL30592071 0.86 CYP11B1 (0.55) SYKAURKBINCENPKDM4EALDH1A1
SCHEMBL12498949 0.86 CYP11B1 (0.55) SYKAURKBINCENPKDM4EALDH1A1
SCHEMBL29894839 0.85 CA1 (0.50) SYKAURKBINCENPKDM4EALDH1A1
SCHEMBL5702570 0.85 CA1 (0.50) SYKAURKBINCENPKDM4EALDH1A1
SCHEMBL15674490 0.85 SYK (0.49) SYKAURKBINCENPKDM4EALDH1A1
SCHEMBL10131329 0.83 SYK (0.48) SYKAURKBINCENPKDM4EALDH1A1
SCHEMBL3865219 0.83 SYK (0.48) SYKAURKBINCENPKDM4EALDH1A1
SCHEMBL4881988 0.83 CYP2A6 (0.61) KDM4EALDH1A1GAACYP11B1CYP11B2
SCHEMBL30199921 0.83 CYP2A6 (0.61) KDM4EALDH1A1GAACYP11B1CYP11B2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 449 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2278637-B2 Complexes of form L2MX UNIV PRINCETON (US) 2021-06-09 EP claimed
EP-2499181-B1 POLYMER FOR OPTOELECTRONIC DEVICE BOE TECHNOLOGY GROUP CO LTD (CN) 2020-05-13 EP claimed
US-10629827-B2 Organometallic complexes as phosphorescent emitters in organic LEDs THE TRUSTEES OF PRINCETON UNIVERSITY (US) 2020-04-21 US claimed
EP-1933395-B2 Complexes of form L2IrX UNIV PRINCETON (US) 2019-08-07 EP claimed
EP-3379591-A1 COMPLEXES OF FORM L2MX The Trustees of Princeton University (US) 2018-09-26 EP claimed
EP-2911211-B1 COMPLEXES OF FORM L2MX UNIV PRINCETON (US) 2018-05-02 EP claimed
EP-1252803-B2 COMPLEXES OF FORM L2MX AS PHOSPHORESCENT DOPANTS FOR ORGANIC LEDS UNIV PRINCETON (US) 2015-09-02 EP claimed
EP-2911211-A1 COMPLEXES OF FORM L2MX The Trustees of Princeton University (US) 2015-08-26 EP claimed
EP-2278637-B1 Complexes of form L2MX UNIV PRINCETON (US) 2015-02-25 EP claimed
EP-2139929-B1 POLYCARBAZOLYL(METH)ACRYLATE LIGHT EMISSIVE COMPOSITIONS GEN ELECTRIC (US) 2014-10-08 EP claimed
US-20060029829-A1 Organometallic complexes as phosphorescent emitters in organic LEDS THOMPSON MARK E 2006-02-09 US claimed
CN-1224297-C L as phosphorescent dopant for organic light emitting devices2Complexes of the MX form UNIV PRINCETON (US) 2005-10-19 CN claimed
US-6902830-B2 Organometallic complexes as phosphorescent emitters in organic LEDs THE TRUSTEES OF PRINCETON UNIVERSITY (US) 2005-06-07 US claimed
US-20040262576-A1 Organometallic complexes as phosphorescent emitters in organic LEDs THOMPSON MARK E (US) 2004-12-30 US claimed
CN-1413426-A Complexes in the form of phosphorescent dopants L2MX as organic light-emitting devices UNIV PRINCETON (US) 2003-04-23 CN claimed
EP-1252803-A4 COMPLEXES OF FORM L 2?MX AS PHOSPHORESCENT DOPANTS FOR ORGANIC LEDS UNIV PRINCETON (US) 2003-04-16 EP claimed
US-20030017361-A1 Organometallic complexes as phosphorescent emitters in organic LEDs THOMPSON MARK E (US) 2003-01-23 US claimed
EP-1252803-A1 COMPLEXES OF FORM L 2?MX AS PHOSPHORESCENT DOPANTS FOR ORGANIC LEDS THE TRUSTEES OF PRINCETON UNIVERSITY (US) 2002-10-30 EP claimed
US-20020034656-A1 Organometallic complexes as phosphorescent emitters in organic LEDs THE UNIVERSITY OF SOUTHERN CALIFORNIA 2002-03-21 US claimed
WO-2001041512-A1 COMPLEXES OF FORM L2MX AS PHOSPHORESCENT DOPANTS FOR ORGANIC LEDS THE TRUSTEES OF PRINCETON UNIVERSITY (US) 2001-06-07 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10629827-B2 Organometallic complexes as phosphorescent emitters in organic LEDs MLX, L1CAM, POU5F1 SYK 3672/4885AURKB 1170/4885INCENP 1029/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.