Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MC4R | P32245 | 6/20 | 0.60 |
| ▸ | MC5R | P33032 | 4/20 | 0.60 |
| ▸ | MC3R | P41968 | 4/20 | 0.60 |
| ▸ | CSNK1E | P49674 | 1/20 | 0.50 |
| ▸ | ALPI | P09923 | 1/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.50 |
| ▸ | XIAP | P98170 | 1/20 | 0.50 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.50 |
| ▸ | CNR2 | P34972 | 1/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.47 |
| ▸ | TYR | P14679 | 2/20 | 0.46 |
| ▸ | LTA4H | P09960 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9439526 | 0.97 | MC4R (0.57) | MC4RMC5RMC3RCSNK1EALPI | |
| SCHEMBL24785636 | 0.94 | MC4R (0.56) | MC4RMC5RMC3RCSNK1EALPI | |
| SCHEMBL9572329 | 0.92 | MC4R (0.55) | MC4RMC5RMC3RCSNK1EALPI | |
| SCHEMBL9872582 | 0.88 | ALPI (0.56) | MC4RMC5RMC3RALPIPKM | |
| Hydrochloric Acid SCHEMBL9535635 | 0.86 | LTA4H (0.50) | MC4RMC5RMC3RPTGS1LTA4H | |
| Hydrochloric Acid SCHEMBL9439232 | 0.84 | SLC7A5 (0.50) | MC4RMC5RMC3RPTGS1SLC7A5 | |
| SCHEMBL9752170 | 0.83 | MC4R (0.67) | MC4RMC5RMC3R | |
| SCHEMBL8684999 | 0.82 | SLC1A1 (0.57) | MC4RMC5RMC3RCSNK1EALPI | |
| SCHEMBL9044380 | 0.82 | MC4R (0.48) | MC4RMC5RMC3RPTGS1SLC7A5 | |
| Hydrochloric Acid SCHEMBL9439245 | 0.82 | MC4R (0.65) | MC4RMC5RMC3R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5654451-A | GUANIDINE AND/OR NITROGUANIDINE-CONTAINING BIS/DI- OR TRIPEPTIDES/ COUPLED BY A DIAMINE; VIRICIDES; ANTIPROTOZOA AGENTS; FUNGICIDES; PARASITICIDES; DRUG DELIVERY; MEMBRANE TRANSPORTATION | MAGAININ PHARMACEUTICALS INC. (US) | 1997-08-05 | — | — | US | disclosed |