Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 1/20 | 0.41 |
| ▸ | NQO2 | P16083 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | CASP1 | P29466 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | CASP7 | P55210 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | HTR6 | P50406 | 1/20 | 0.36 |
| ▸ | JAK2 | O60674 | 1/20 | 0.34 |
| ▸ | BTK | Q06187 | 1/20 | 0.34 |
| ▸ | EGFR | P00533 | 1/20 | 0.33 |
| ▸ | SRC | P12931 | 1/20 | 0.33 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.33 |
| ▸ | CCR6 | P51684 | 1/20 | 0.33 |
| ▸ | METAP1 | P53582 | 3/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9870767 | 0.83 | MEN1 (0.34) | KDM4EALDH1A1HPGDGAAHTR6 | |
| SCHEMBL9871149 | 0.79 | CYP3A4 (0.38) | ALDH1A1HTR6METAP1CYP1A2CYP3A4 | |
| Hydrochloric Acid SCHEMBL9872164 | 0.78 | METAP1 (0.39) | ALDH1A1HTR6METAP1CYP1A2CYP3A4 | |
| SCHEMBL9873935 | 0.78 | KCNH2 (0.48) | CYP19A1NQO2KDM4EALDH1A1HPGD | |
| SCHEMBL9871416 | 0.76 | METAP1 (0.45) | KDM4EALDH1A1HPGDHTTHSD17B10 | |
| SCHEMBL9879138 | 0.76 | METAP1 (0.45) | HTR6EGFRHSP90AA1CCR6METAP1 | |
| Hydrochloric Acid SCHEMBL9873069 | 0.75 | METAP1 (0.46) | KDM4EALDH1A1HPGDHTTHSD17B10 | |
| SCHEMBL9870438 | 0.72 | CYP19A1 (0.48) | CYP19A1NQO2KDM4EALDH1A1HPGD | |
| SCHEMBL9870845 | 0.68 | CYP3A4 (0.39) | ALDH1A1HTR6METAP1CYP1A2CYP3A4 | |
| Hydrochloric Acid SCHEMBL9872392 | 0.68 | CYP3A4 (0.39) | ALDH1A1HTR6METAP1CYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5030646-A | Treatment of diseases resulting from disfunction of seretoninergic system | ADIR ET COMPAGNIE (FR) | 1991-07-09 | — | — | US | disclosed |