Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | METAP1 | P53582 | 3/20 | 0.45 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.38 |
| ▸ | CCR6 | P51684 | 1/20 | 0.38 |
| ▸ | HTR6 | P50406 | 9/20 | 0.37 |
| ▸ | EGFR | P00533 | 1/20 | 0.36 |
| ▸ | KAT2B | Q92831 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9871416 | 0.91 | METAP1 (0.45) | METAP1KCNA5KCNH2HSP90AA1CCR6 | |
| Hydrochloric Acid SCHEMBL9873069 | 0.90 | METAP1 (0.46) | METAP1KCNA5KCNH2HSP90AA1CCR6 | |
| SCHEMBL9871149 | 0.82 | CYP3A4 (0.38) | METAP1KCNH2HTR6 | |
| Hydrochloric Acid SCHEMBL9872164 | 0.81 | METAP1 (0.39) | METAP1KCNH2HTR6 | |
| SCHEMBL9871826 | 0.78 | CYP3A4 (0.48) | KCNH2EGFR | |
| SCHEMBL9872735 | 0.76 | CYP19A1 (0.41) | METAP1HSP90AA1CCR6HTR6EGFR | |
| SCHEMBL9870767 | 0.76 | MEN1 (0.34) | METAP1HSP90AA1CCR6HTR6 | |
| SCHEMBL9870845 | 0.73 | CYP3A4 (0.39) | METAP1KCNH2HTR6 | |
| Hydrochloric Acid SCHEMBL9872392 | 0.72 | CYP3A4 (0.39) | METAP1KCNH2HTR6 | |
| SCHEMBL9872175 | 0.72 | KDM4E (0.48) | EGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5030646-A | Treatment of diseases resulting from disfunction of seretoninergic system | ADIR ET COMPAGNIE (FR) | 1991-07-09 | — | — | US | disclosed |