Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.33 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.33 |
| ▸ | CCR6 | P51684 | 1/20 | 0.33 |
| ▸ | METAP1 | P53582 | 5/20 | 0.33 |
| ▸ | HTR6 | P50406 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | ACHE | P22303 | 1/20 | 0.31 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.31 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9872568 | 0.83 | CHRNA7 (0.43) | MEN1POLBMAPTKMT2AALDH1A1 | |
| SCHEMBL9872735 | 0.83 | CYP19A1 (0.41) | MAPTHSP90AA1CCR6METAP1HTR6 | |
| SCHEMBL9871319 | 0.82 | CHRNA7 (0.44) | MEN1POLBMAPTKMT2AMETAP1 | |
| SCHEMBL9872040 | 0.80 | CDK5 (0.34) | MEN1POLBMAPTALOX15RECQL | |
| SCHEMBL9871149 | 0.79 | CYP3A4 (0.38) | MEN1RECQLKMT2AMETAP1HTR6 | |
| Hydrochloric Acid SCHEMBL9872164 | 0.78 | METAP1 (0.39) | METAP1HTR6ALDH1A1 | |
| SCHEMBL9870860 | 0.78 | KCNH2 (0.48) | MEN1POLBMAPTALOX15RECQL | |
| SCHEMBL9871416 | 0.76 | METAP1 (0.45) | MEN1MAPTKMT2AL3MBTL1HSP90AA1 | |
| SCHEMBL9879138 | 0.76 | METAP1 (0.45) | HSP90AA1CCR6METAP1HTR6 | |
| Hydrochloric Acid SCHEMBL9873069 | 0.75 | METAP1 (0.46) | MEN1MAPTKMT2AL3MBTL1HSP90AA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5030646-A | Treatment of diseases resulting from disfunction of seretoninergic system | ADIR ET COMPAGNIE (FR) | 1991-07-09 | — | — | US | disclosed |