Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR7 | P34969 | 5/20 | 0.54 |
| ▸ | HTR1A | P08908 | 3/20 | 0.52 |
| ▸ | DRD2 | P14416 | 3/20 | 0.52 |
| ▸ | HTR2A | P28223 | 3/20 | 0.52 |
| ▸ | HTR6 | P50406 | 3/20 | 0.52 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.52 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.52 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.52 |
| ▸ | DRD4 | P21917 | 1/20 | 0.52 |
| ▸ | HTR2C | P28335 | 1/20 | 0.52 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.52 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.52 |
| ▸ | HRH1 | P35367 | 1/20 | 0.52 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.52 |
| ▸ | DRD3 | P35462 | 1/20 | 0.52 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.52 |
| ▸ | HTR5A | P47898 | 1/20 | 0.52 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.52 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.52 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9757518 | 0.80 | CYP2D6 (0.62) | HTR7HTR1ADRD2HTR2AADRA2A | |
| SCHEMBL9757165 | 0.77 | HTR7 (0.66) | HTR7HTR1ADRD2HTR2AHTR6 | |
| SCHEMBL9757424 | 0.75 | HTR7 (0.72) | HTR7HTR1ADRD2HTR2AHTR6 | |
| SCHEMBL9635334 | 0.73 | HTR7 (0.66) | HTR7HTR1ADRD2HTR2AHTR6 | |
| SCHEMBL9757388 | 0.73 | HTR7 (0.66) | HTR7HTR1ADRD2HTR2AHTR6 | |
| SCHEMBL9757519 | 0.73 | HTR7 (0.95) | HTR7HTR1ADRD2HTR2AHTR6 | |
| SCHEMBL9757255 | 0.72 | HTR7 (0.80) | HTR7HTR1ADRD2HTR2AHTR6 | |
| SCHEMBL9757250 | 0.72 | HTR7 (0.66) | HTR7HTR1ADRD2HTR2AHTR6 | |
| SCHEMBL9636875 | 0.72 | HTR7 (0.56) | HTR7HTR1ADRD2HTR2AHTR6 | |
| SCHEMBL9635468 | 0.71 | HTR7 (0.55) | HTR7HTR1ADRD2HTR2AHTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5021420-A | Antiserotonine agents; central nervous system, gastroin-testinal and cardiovascular disorders | RHONE-POULENC SANTE (FR) | 1991-06-04 | — | — | US | disclosed |