Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.55 |
| ▸ | HPGD | P15428 | 2/20 | 0.55 |
| ▸ | NPC1 | O15118 | 2/20 | 0.55 |
| ▸ | RAB9A | P51151 | 2/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | PHGDH | O43175 | 1/20 | 0.32 |
| ▸ | MGLL | Q99685 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4679699 | 0.78 | MEN1 (0.41) | SMN1; SMN2HPGDNPC1RAB9AMAPT | |
| SCHEMBL9862074 | 0.75 | NPC1 (0.55) | SMN1; SMN2HPGDNPC1RAB9AKDM4E | |
| SCHEMBL29417850 | 0.72 | NPC1 (0.96) | SMN1; SMN2HPGDNPC1RAB9ALMNA | |
| SCHEMBL30421152 | 0.63 | NPC1 (0.42) | SMN1; SMN2HPGDNPC1RAB9AKDM4E | |
| SCHEMBL9528239 | 0.63 | NPC1 (0.42) | SMN1; SMN2HPGDNPC1RAB9AKDM4E | |
| SCHEMBL6272216 | 0.61 | SIGMAR1 (0.41) | SMN1; SMN2HPGDNPC1RAB9AKDM4E | |
| SCHEMBL8756913 | 0.61 | HPGD (0.40) | SMN1; SMN2HPGDNPC1RAB9AKDM4E | |
| SCHEMBL16361136 | 0.61 | HPGD (0.40) | SMN1; SMN2HPGDNPC1RAB9AKDM4E | |
| SCHEMBL105023 | 0.61 | SIGMAR1 (0.41) | SMN1; SMN2HPGDNPC1RAB9AKDM4E | |
| SCHEMBL3861449 | 0.60 | MAPT (0.41) | SMN1; SMN2HPGDNPC1RAB9AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5073186-A | 5-THIOXO-2-IMIDAZOLINYL BENZOIC ACIDS, ESTERS, SALTS & RELATED COMPOUNDS, AND USE THEREOF AS HERBICIDAL AGENTS | AMERICAN CYANAMID COMPANY (US) | 1991-12-17 | — | — | US | disclosed |
| US-4911747-A | Applying to (mono- or di-)cotyledonous plant, or soil | AMERICAN CYANAMID CO. (US) | 1990-03-27 | — | — | US | disclosed |
| EP-0135711-B1 | 5-THIOXO-2-IMIDAZOLINYL BENZOIC ACIDS, ESTERS, SALTS AND RELATED COMPOUNDS, AND USE THEREOF AS HERBICIDAL AGENTS | AMERICAN CYANAMID COMPANY (US) | 1989-08-09 | — | — | EP | disclosed |
| EP-0135711-A1 | 5-thioxo-2-imidazolinyl benzoic acids, esters, salts and related compounds, and use thereof as herbicidal agents | AMERICAN CYANAMID COMPANY (US) | 1985-04-03 | — | — | EP | disclosed |