Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.55 |
| ▸ | RAB9A | P51151 | 3/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.55 |
| ▸ | HPGD | P15428 | 1/20 | 0.55 |
| ▸ | GAA | P10253 | 4/20 | 0.39 |
| ▸ | MEN1 | O00255 | 4/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | MGLL | Q99685 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.35 |
| ▸ | DRD3 | P35462 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7394385 | 0.78 | HSP90AA1 (0.46) | NPC1RAB9ASMN1; SMN2HPGDGAA | |
| SCHEMBL7439040 | 0.78 | L3MBTL1 (0.49) | NPC1RAB9AGAAMEN1KMT2A | |
| SCHEMBL9872899 | 0.75 | SMN1; SMN2 (0.55) | NPC1RAB9ASMN1; SMN2HPGDGAA | |
| SCHEMBL8779304 | 0.73 | ALDH1A1 (0.45) | GAAMEN1KMT2AMAPTTDP1 | |
| SCHEMBL9091364 | 0.73 | SMN1; SMN2 (0.44) | SMN1; SMN2GAAKDM4EMAPTALDH1A1 | |
| SCHEMBL7393404 | 0.73 | MEN1 (0.52) | SMN1; SMN2HPGDMEN1KMT2AKDM4E | |
| SCHEMBL7395463 | 0.72 | POLB (0.44) | NPC1RAB9AMEN1KMT2AMAPT | |
| SCHEMBL2424631 | 0.72 | NPC1 (0.96) | NPC1RAB9ASMN1; SMN2HPGDMEN1 | |
| SCHEMBL29417850 | 0.72 | NPC1 (0.96) | NPC1RAB9ASMN1; SMN2HPGDMEN1 | |
| SCHEMBL9528239 | 0.71 | NPC1 (0.42) | NPC1RAB9ASMN1; SMN2HPGDGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0431545-A2 | Selectif herbicidal agent and fungicidal agent | Hoechst Schering AgrEvo GmbH (DE) | 1991-06-12 | — | — | EP | disclosed |
| EP-0133310-B1 | IMIDAZOLIDINONES, AND IMIDAZOLIDINETHIONES, PROCESS FOR THE PREPARATION THEREOF, AND USE OF SAID COMPOUNDS AS HERBICIDAL AGENTS | AMERICAN CYANAMID COMPANY (US) | 1988-09-14 | — | — | EP | disclosed |
| US-4608079-A | Imidazolidinones, and imidazolidinethiones, process and intermediates for the preparation thereof, and use of said compounds as herbicidal agents | AMERICAN CYANAMID COMPANY (US) | 1986-08-26 | — | — | US | disclosed |
| US-4554013-A | Herbicidal imidazolinyl naphthoic acids | AMERICAN CYANAMID COMPANY (US) | 1985-11-19 | — | — | US | disclosed |
| EP-0133310-A1 | Imidazolidinones, and imidazolidinethiones, process for the preparation thereof, and use of said compounds as herbicidal agents | AMERICAN CYANAMID COMPANY (US) | 1985-02-20 | — | — | EP | disclosed |
| EP-0133311-A2 | Substituted imidazolinyl benzoic acids, esters and salts and use thereof as herbicidal agents | AMERICAN CYANAMID COMPANY (US) | 1985-02-20 | — | — | EP | disclosed |