SCHEMBL9872974

SCHEMBL9872974

C=CC(=O)OC(C)CC(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)F

nearest known ligand 0.36

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4396356 1.00 TSHR (0.36) TSHR
SCHEMBL11648227 0.87 HCAR2 (0.35)
SCHEMBL10457703 0.85 HCAR2 (0.36)
SCHEMBL28014880 0.85 TSHR (0.34) TSHR
SCHEMBL8601132 0.84 TSHR (0.31) TSHR
SCHEMBL449783 0.84 TSHR (0.31) TSHR
SCHEMBL3125065 0.84 TSHR (0.31) TSHR
SCHEMBL6847445 0.82 TSHR (0.32) TSHR
SCHEMBL11853997 0.82 HCAR2 (0.46)
SCHEMBL20538783 0.81 ALDH1A1 (0.31) TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4985473-A POLY/FLUOROOXYALKYLENE/URETHANES MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1991-01-15 US disclosed
EP-0040923-B1 COMPOSITIONS FOR PROVIDING ABHERENT COATINGS; POLY (FLUOROOYALKYLENE) URETHANE ACRYLATES MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1985-05-02 EP disclosed
US-4383878-A RELEASE COATING OF RADIATION CURED POLYFLUORINATED ACRYLATE MONOMER, CURING AGENT AND POLYMER MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1983-05-17 US disclosed
US-4321404-A Compositions for providing abherent coatings MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1982-03-23 US disclosed