Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDPK1 | O15530 | 2/20 | 0.60 |
| ▸ | MTOR | P42345 | 1/20 | 0.60 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | ANPEP | P15144 | 1/20 | 0.38 |
| ▸ | LAP3 | P28838 | 1/20 | 0.38 |
| ▸ | SRC | P12931 | 1/20 | 0.38 |
| ▸ | ELANE | P08246 | 1/20 | 0.36 |
| ▸ | BCHE | P06276 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | FUCA1 | P04066 | 1/20 | 0.35 |
| ▸ | KLK1 | P06870 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13109619 | 0.86 | PDPK1 (0.68) | PDPK1MTORTSHRSRCBCHE | |
| SCHEMBL5830234 | 0.84 | PDPK1 (0.65) | PDPK1MTORTSHRSRCELANE | |
| SCHEMBL13109573 | 0.84 | PDPK1 (0.65) | PDPK1MTORTSHRSRCELANE | |
| SCHEMBL9874053 | 0.83 | PDPK1 (0.63) | PDPK1MTORTSHRSRCELANE | |
| SCHEMBL7720528 | 0.81 | PDPK1 (0.65) | PDPK1MTORTSHRSRCELANE | |
| SCHEMBL20197201 | 0.80 | PDPK1 (0.59) | PDPK1MTORTSHRBCHEALDH1A1 | |
| SCHEMBL989579 | 0.80 | PDPK1 (0.59) | PDPK1MTORTSHRBCHEALDH1A1 | |
| SCHEMBL6822201 | 0.80 | PDPK1 (0.59) | PDPK1MTORTSHRBCHEALDH1A1 | |
| SCHEMBL7739055 | 0.80 | PDPK1 (0.59) | PDPK1MTORTSHRBCHEALDH1A1 | |
| SCHEMBL7261299 | 0.80 | PDPK1 (0.59) | PDPK1MTORTSHRBCHEALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5055597-A | SYNTHESIS OF INOSITOL PHOSPHATES | MERCK SHARP & DOHME LTD. (GB) | 1991-10-08 | — | — | US | disclosed |
| US-4906761-A | Myo-inositol orthoformates | MERCK SHARPE & DOHME LTD. (GB) | 1990-03-06 | — | — | US | disclosed |