Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 6/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.43 |
| ▸ | POLB | P06746 | 3/20 | 0.42 |
| ▸ | HTT | P42858 | 3/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.41 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | MIF | P14174 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11779421 | 0.79 | MAPK1 (0.43) | MAPTALDH1A1HPGDMAPK1USP2 | |
| SCHEMBL11074949 | 0.77 | MAPT (0.51) | MAPTALDH1A1HPGDMAPK1USP2 | |
| SCHEMBL1101916 | 0.77 | ALDH1A1 (0.54) | MAPTALDH1A1HPGDMAPK1USP2 | |
| SCHEMBL11556953 | 0.74 | ALDH1A1 (0.62) | MAPTALDH1A1HPGDMAPK1MEN1 | |
| SCHEMBL17156221 | 0.74 | MIF (0.68) | MAPTALDH1A1HPGDMAPK1USP2 | |
| SCHEMBL11192533 | 0.71 | MAPT (0.53) | MAPTALDH1A1HPGDMAPK1MEN1 | |
| SCHEMBL19499958 | 0.71 | NPSR1 (0.52) | MAPTALDH1A1MAPK1MEN1KMT2A | |
| SCHEMBL2149849 | 0.70 | ALDH1A1 (0.53) | MAPTALDH1A1HPGDUSP2TSHR | |
| SCHEMBL11196544 | 0.70 | HPGD (0.69) | MAPTALDH1A1HPGDMAPK1USP2 | |
| SCHEMBL6743259 | 0.70 | ALDH1A1 (0.58) | MAPTALDH1A1HPGDMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5019611-A | Tetrahydrotriazinethiones | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1991-05-28 | — | — | US | disclosed |
| EP-0278890-A2 | Non-staining and slightly-staining antiozonants | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1988-08-17 | — | — | EP | disclosed |