Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 6/20 | 0.51 |
| ▸ | AGTR2 | P50052 | 2/20 | 0.50 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9874341 | 0.94 | PPARG (0.49) | PPARGAGTR2AGTR1 | |
| SCHEMBL9873738 | 0.89 | AGTR2 (0.63) | AGTR2AGTR1 | |
| SCHEMBL9872308 | 0.86 | PPARG (0.52) | PPARGAGTR2AGTR1 | |
| SCHEMBL9873900 | 0.84 | AGTR1 (0.41) | AGTR2AGTR1 | |
| SCHEMBL9871352 | 0.84 | PPARG (0.48) | PPARGAGTR2AGTR1 | |
| SCHEMBL9873573 | 0.84 | PPARG (0.52) | PPARG | |
| SCHEMBL9873219 | 0.83 | AGTR2 (0.60) | AGTR2AGTR1 | |
| SCHEMBL9874524 | 0.82 | PPARG (0.54) | PPARG | |
| SCHEMBL9873192 | 0.82 | PPARG (0.51) | PPARG | |
| SCHEMBL9872978 | 0.82 | PPARG (0.53) | PPARGAGTR2AGTR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1991019715-A1 | 1H-SUBSTITUTED-IMIDAZO[4,5-d]PYRIDAZINE COMPOUNDS FOR TREATMENT OF CARDIOVASCULAR DISORDERS | G.D. SEARLE & CO. (US) | 1991-12-26 | — | — | WO | disclosed |