Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 6/20 | 0.53 |
| ▸ | CACNA1C | Q13936 | 6/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 5/20 | 0.53 |
| ▸ | MAPT | P10636 | 5/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 4/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.53 |
| ▸ | TSHR | P16473 | 3/20 | 0.53 |
| ▸ | NFKB1 | P19838 | 3/20 | 0.53 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | CACNA1F | O60840 | 3/20 | 0.41 |
| ▸ | CACNA1D | Q01668 | 3/20 | 0.41 |
| ▸ | CACNA1S | Q13698 | 3/20 | 0.41 |
| ▸ | ABCC4 | O15439 | 2/20 | 0.41 |
| ▸ | ABCB11 | O95342 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.41 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9875222 | 0.88 | CACNA1C (0.56) | ADORA3CACNA1CCYP1A2MAPTCYP3A4 | |
| SCHEMBL10516018 | 0.88 | MAPT (0.43) | ADORA3CACNA1CCYP1A2MAPTCYP3A4 | |
| SCHEMBL9879777 | 0.88 | NR1I2 (0.54) | ADORA3CACNA1CCYP1A2MAPTCYP3A4 | |
| SCHEMBL11005379 | 0.87 | CYP1A2 (0.71) | ADORA3CACNA1CCYP1A2MAPTCYP3A4 | |
| SCHEMBL9876069 | 0.87 | CACNA1C (0.55) | ADORA3CACNA1CCYP1A2MAPTCYP3A4 | |
| SCHEMBL9876125 | 0.86 | CACNA1C (0.54) | ADORA3CACNA1CCYP1A2MAPTCYP3A4 | |
| SCHEMBL9875740 | 0.86 | CACNA1C (0.54) | ADORA3CACNA1CCYP1A2MAPTCYP3A4 | |
| SCHEMBL9875212 | 0.86 | CACNA1C (0.54) | ADORA3CACNA1CCYP1A2MAPTCYP3A4 | |
| SCHEMBL11009095 | 0.84 | ADORA3 (0.74) | ADORA3CACNA1CCYP1A2MAPTCYP3A4 | |
| SCHEMBL9879946 | 0.83 | CACNA1C (0.50) | ADORA3CACNA1CCYP1A2MAPTCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5008279-A | Circulation-active fluoromethoxyphenyl dihydropyridine compounds | BAYER AKTIENGESELLSCHAFT (DE) | 1991-04-16 | — | — | US | disclosed |