SCHEMBL987344

SCHEMBL987344

COc1ccc(Oc2ccc(Cl)cc2)cc1

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LTA4H P09960 2/20 0.61
HPGD P15428 2/20 0.59
MAOA P21397 1/20 0.58
MAOB P27338 1/20 0.58
CA12 O43570 1/20 0.58
CA1 P00915 1/20 0.58
CA2 P00918 1/20 0.58
CA7 P43166 1/20 0.58
CA9 Q16790 1/20 0.58
CA14 Q9ULX7 1/20 0.58
ALDH1A1 P00352 2/20 0.52
MEN1 O00255 1/20 0.52
KMT2A Q03164 1/20 0.52
PARP10 Q53GL7 1/20 0.48
ACHE P22303 1/20 0.48
NPBWR1 P48145 2/20 0.47
NPC1 O15118 1/20 0.47
RAB9A P51151 1/20 0.47
SMN1; SMN2 Q16637 1/20 0.47
AHR P35869 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2226770 0.92
SCHEMBL154527 0.92
Chloromethane SCHEMBL9703019 0.89 CA1 (0.65) HPGDMAOAMAOBCA12CA1
SCHEMBL29069477 0.89 CA1 (0.65) HPGDMAOAMAOBCA12CA1
SCHEMBL28525728 0.89 CA1 (0.65) HPGDMAOAMAOBCA12CA1
Water SCHEMBL9443323 0.89 CA1 (0.65) HPGDMAOAMAOBCA12CA1
SCHEMBL4444134 0.89 CA1 (0.65) HPGDMAOAMAOBCA12CA1
Iodide SCHEMBL5695908 0.89 CA1 (0.65) HPGDMAOAMAOBCA12CA1
Hydrochloric Acid SCHEMBL11293911 0.89 CA1 (0.65) HPGDMAOAMAOBCA12CA1
Water SCHEMBL28888589 0.89 CA1 (0.65) HPGDMAOAMAOBCA12CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 49 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023128696-A1 NOVEL METHOD FOR PREPARING SUBSTITUTED 1-HYDROXY-2-PYRIDONE COMPOUND 주식회사 케이씨아이 2023-07-06 WO claimed
US-20130203822-A1 COMPOUNDS FOR TREATMENT OF TUMORS BEARING DEREGULATED MYC ONCOPROTEINS QUATTRONE ALESSANDRO (IT) 2013-08-08 US claimed
EP-2590648-A2 COMPOUNDS FOR TREATMENT OF TUMORS BEARING DEREGULATED MYC ONCOPROTEINS Quattrone, Alessandro (IT) 2013-05-15 EP claimed
WO-2011161631-A2 COMPOUNDS FOR TREATMENT OF TUMORS BEARING DEREGULATED MYC ONCOPROTEINS QUATTRONE ALESSANDRO (IT) 2011-12-29 WO claimed
WO-2011011598-A1 PROCESS FOR PREPARING 4- { (S) -2- (4-(4-CHLOROPHENOXY) PHENOXYMETHYL) PYRROLIDIN-1-YL) } BUTYRIC ACID AND SALTS THEREOF DECODE GENETICS EHF (IS) 2011-01-27 WO claimed
US-5817825-A Process for the preparation of 1-hydroxy-2-pyridones HOECHST AKTIENGESELLSCHAFT (DE) 1998-10-06 US claimed
EP-0710650-B1 Process for the preparation of 1-hydroxy-2-pyridones HOECHST AG (DE) 1998-08-26 EP claimed
EP-0710650-A2 Process for the preparation of 1-hydroxy-2-pyridones HOECHST AKTIENGESELLSCHAFT (DE) 1996-05-08 EP claimed
WO-2023128696-A1 NOVEL METHOD FOR PREPARING SUBSTITUTED 1-HYDROXY-2-PYRIDONE COMPOUND 주식회사 케이씨아이 2023-07-06 WO disclosed
US-11548900-B2 Oxazino-quinazoline and oxazino-quinoline type compound, preparation method and uses thereof BEIJING SCITECH-MQ PHARMACEUTICALS LIMITED (CN) 2023-01-10 US disclosed
EP-3760633-B1 OXAZINO-QUINAZOLINE AND OXAZINO-QUINAZOLINE TYPE COMPOUND, PREPARATION METHOD THEREFOR, AND USES THEREOF BEIJING SCITECH MQ PHARMACEUTICALS LTD (CN) 2021-12-15 EP disclosed
US-20210040114-A1 OXAZINO-QUINAZOLINE AND OXAZINO-QUINOLINE TYPE COMPOUND, PREPARATION METHOD AND USES THEREOF ACCSALUS BIOSCIENCES LIMITED (VG) 2021-02-11 US disclosed
EP-3760633-A1 OXAZINO-QUINAZOLINE AND OXAZINO-QUINAZOLINE TYPE COMPOUND, PREPARATION METHOD THEREFOR, AND USES THEREOF Beijing Scitech-MQ Pharmaceuticals Limited (CN) 2021-01-06 EP disclosed
WO-2019170088-A1 OXAZINO-QUINAZOLINE AND OXAZINO-QUINAZOLINE TYPE COMPOUND, PREPARATION METHOD THEREFOR, AND USES THEREOF 北京赛特明强医药科技有限公司 2019-09-12 WO disclosed
EP-0303415-A2 Herbicidally active phenoxy-alkanecarboxylic acid derivatives SUNTORY LIMITED (JP) 1989-02-15 EP disclosed
US-4391995-A 4-Phenoxy-phenoxy-alkane-carboxylic acid derivatives and process for their manufacture HOECHST AKTIENGESELLSCHAFT (DE) 1983-07-05 US disclosed
US-4301295-A ANTILIPEMIC AND ANTICHOLESTEROL AGENTS HOECHST AKTIENGESELLSCHAFT (DE) 1981-11-17 US disclosed
US-4238626-A ANTICHOLESTEROL AND ANTILIPEMIC AGENTS HOECHST AKTIENGESELLSCHAFT (DE) 1980-12-09 US disclosed
US-4156011-A TREATMENT OF CARDIOVASCULAR DISORDERS SOCIETE ANONYME DITE: LABORATOIRE L. LAFON (FR) 1979-05-22 US disclosed
US-4042603-A SUBSTITUTED DIBENZOFURAN OR 9-FLUORENONE FROM A DIPHENYL ETHER OR BENZOPHENONE UBE INDUSTRIES, LTD. (JA) 1977-08-16 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130203822-A1 COMPOUNDS FOR TREATMENT OF TUMORS BEARING DEREGULATED MYC ONCOPROTEINS MYC, MYCBP, BCOR LTA4H 4677/4885HPGD 4714/4885MAOA 3409/4885
US-11548900-B2 Oxazino-quinazoline and oxazino-quinoline type compound, preparation method and uses thereof WNK1, WNK2, WNK3 LTA4H 2936/4885HPGD 702/4885MAOA 1220/4885
US-20210040114-A1 OXAZINO-QUINAZOLINE AND OXAZINO-QUINOLINE TYPE COMPOUND, PREPARATION METHOD AND USES THEREOF WNK1, WNK2, WNK3 LTA4H 2936/4885HPGD 702/4885MAOA 1220/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.