SCHEMBL987786

SCHEMBL987786

CCc1cccc(CC)c1N1C(=O)c2ccc(C)cc2C1=O

nearest known ligand 0.70

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ANPEP P15144 6/20 0.70
DPP4 P27487 5/20 0.70
CRHBP P24387 1/20 0.48
CRHR2 Q13324 1/20 0.48
CA9 Q16790 3/20 0.47
CA12 O43570 2/20 0.47
CA1 P00915 2/20 0.47
CA2 P00918 1/20 0.46
LMNA P02545 1/20 0.45
MAPT P10636 1/20 0.45
HTT P42858 1/20 0.45
L3MBTL1 Q9Y468 1/20 0.45
NPC1 O15118 1/20 0.44
ALDH1A1 P00352 1/20 0.44
TSHR P16473 1/20 0.44
CASP1 P29466 1/20 0.44
RAB9A P51151 1/20 0.44
CASP7 P55210 1/20 0.44
HSD17B10 Q99714 1/20 0.44
CHRM2 P08172 2/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10615280 0.84 ANPEP (0.51) ANPEPDPP4CA9CA12CA1
SCHEMBL29382376 0.83 DPP4 (0.68) ANPEPDPP4CRHBPCRHR2LMNA
SCHEMBL987346 0.83 DPP4 (0.68) ANPEPDPP4CRHBPCRHR2LMNA
SCHEMBL9812607 0.83 ANPEP (0.68) ANPEPDPP4CRHBPCRHR2LMNA
SCHEMBL6452471 0.83 ANPEP (1.00) ANPEPDPP4CRHBPCRHR2LMNA
SCHEMBL12665488 0.81 DPP4 (0.71) ANPEPDPP4CA9CA12CA1
SCHEMBL22221562 0.81 ANPEP (0.66) ANPEPDPP4CRHBPCRHR2LMNA
SCHEMBL10613329 0.80 ANPEP (0.47) ANPEPDPP4CA9CA12CA1
SCHEMBL9812679 0.78 ANPEP (0.62) ANPEPDPP4CA9CA12CA1
SCHEMBL29381488 0.77 DPP4 (0.56) ANPEPDPP4CRHBPCRHR2MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 104 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250113829-A1 HIGH MOLECULAR WEIGHT MODIFIED RNA COMPOSITIONS nanoSUR LLC 2025-04-10 US disclosed
EP-4396348-A2 HIGH MOLECULAR WEIGHT MODIFIED DSRNA COMPOSITIONS Nanosur LLC (US) 2024-07-10 EP disclosed
CN-118302524-A High molecular weight modified dsRNA compositions 纳诺索尔公司 2024-07-05 CN disclosed
WO-2023034849-A2 HIGH MOLECULAR WEIGHT MODIFIED dsRNA COMPOSITIONS nanoSUR LLC (US) 2023-03-09 WO disclosed
US-11174480-B2 Post-transcriptionally chemically modified double strand RNAs nanoSUR LLC (US) 2021-11-16 US disclosed
CN-108291055-B Sulfur-containing compounds as solvents 诺华丝国际股份有限公司 2021-07-06 CN disclosed
CN-112707851-A Sulfur-containing compounds as solvents 诺华丝国际股份有限公司 2021-04-27 CN disclosed
US-10988611-B2 Crosslinked polyvinylpyrrolidone compositions ISP INVESTMENTS LLC (US) 2021-04-27 US disclosed
US-10640769-B2 Post-transcriptionally chemically modified double strand RNAs nanoSUR LLC (US) 2020-05-05 US disclosed
US-20200060273-A1 FUNGICIDAL COMPOSITIONS NOVUS INTERNATIONAL, INC. 2020-02-27 US disclosed
EP-0306222-A2 Benzenesulfonanilide derivatives and fungicides for agriculture and horticulture HOKKO CHEMICAL INDUSTRY CO., LTD (JP) 1989-03-08 EP disclosed
US-H303-H GLYCOSIDE-CONTAINING AGRICULTURAL TREATMENT COMPOSITION A. E. STALEY MANUFACTURING COMPANY (US) 1987-07-07 US disclosed
US-H224-H Glycoside-containing agricultural treatment composition A. E. STALEY MANUFACTURING COMPANY (US) 1987-03-03 US disclosed
US-4512989-A IMIDOESTERS OR IMIDOTHIOESTERS HOKKO CHEMICAL INDUSTRY CO., LTD. (JP) 1985-04-23 US disclosed
US-4420486-A Benzoxazolone derivatives, processes for preparation thereof and compositions containing them HOKKO CHEMICAL INDUSTRY CO., LTD. (JP) 1983-12-13 US disclosed
US-4391804-A Imidazole derivatives and fungicidal composition containing the same HOKKO CHEMICAL INDUSTRY COMPANY, LTD. (JP) 1983-07-05 US disclosed
US-4304778-A 4-Aminoquinazoline derivatives having fungicidal, anti-insect and acaricidal properties SANKYO COMPANY LIMITED (JP) 1981-12-08 US disclosed
US-4279908-A Pyridazine derivatives and their use as agricultural fungicides SANKYO COMPANY LIMITED (JP) 1981-07-21 US disclosed
US-4052395-A AGRICULTURAL FUNGICIDAL COMPOSITIONS CONTAINING 6-(SUBSTITUTED PHENYL)-PYRIDAZINONES AND SAID PYRIDAZINONES SANKYO COMPANY LIMITED (JA) 1977-10-04 US disclosed
US-4036631-A Pyrazolone derivatives and their use as herbicides SANKYO COMPANY LIMITED (JA) 1977-07-19 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250113829-A1 HIGH MOLECULAR WEIGHT MODIFIED RNA COMPOSITIONS NSUN2, NSUN3, RNGTT ANPEP 2082/4885DPP4 3240/4885CRHBP 1276/4885
US-11174480-B2 Post-transcriptionally chemically modified double strand RNAs NSUN2, NSUN3, RNGTT ANPEP 3641/4885DPP4 4394/4885CRHBP 1562/4885
US-20200060273-A1 FUNGICIDAL COMPOSITIONS ERG28, CYP51A1, CYP19A1 ANPEP 894/4885DPP4 68/4885CRHBP 4705/4885
US-10640769-B2 Post-transcriptionally chemically modified double strand RNAs NSUN2, NSUN3, RNGTT ANPEP 3641/4885DPP4 4394/4885CRHBP 1562/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.