Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 2/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9873079 | 0.93 | PPARG (0.51) | PPARG | |
| SCHEMBL9874410 | 0.88 | PPARG (0.52) | PPARG | |
| SCHEMBL9874759 | 0.87 | PPARG (0.49) | PPARG | |
| SCHEMBL9873381 | 0.85 | AGTR2 (0.66) | — | |
| SCHEMBL9871745 | 0.85 | PPARG (0.56) | PPARG | |
| SCHEMBL9873573 | 0.85 | PPARG (0.52) | PPARG | |
| SCHEMBL9874062 | 0.85 | PPARG (0.54) | PPARG | |
| SCHEMBL9872887 | 0.83 | PPARG (0.49) | PPARG | |
| SCHEMBL9871788 | 0.83 | PPARG (0.52) | PPARG | |
| SCHEMBL9874055 | 0.83 | AGTR1 (0.53) | PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1991019715-A1 | 1H-SUBSTITUTED-IMIDAZO[4,5-d]PYRIDAZINE COMPOUNDS FOR TREATMENT OF CARDIOVASCULAR DISORDERS | G.D. SEARLE & CO. (US) | 1991-12-26 | — | — | WO | disclosed |