Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNE2 | O96020 | 8/20 | 0.41 |
| ▸ | CCNE1 | P24864 | 8/20 | 0.41 |
| ▸ | CDK2 | P24941 | 8/20 | 0.41 |
| ▸ | CCNB2 | O95067 | 4/20 | 0.40 |
| ▸ | CDK1 | P06493 | 4/20 | 0.40 |
| ▸ | CCNB1 | P14635 | 4/20 | 0.40 |
| ▸ | CCNB3 | Q8WWL7 | 4/20 | 0.40 |
| ▸ | KCNQ3 | O43525 | 1/20 | 0.38 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.38 |
| ▸ | CDK7 | P50613 | 1/20 | 0.38 |
| ▸ | CCNH | P51946 | 1/20 | 0.38 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.36 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.36 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9874377 | 0.87 | CCNE2 (0.40) | CCNE2CCNE1CDK2CCNB2CDK1 | |
| SCHEMBL1915278 | 0.72 | AKR1C3 (0.47) | AKR1C3MEN1KMT2ANR4A1ALDH1A1 | |
| SCHEMBL9873291 | 0.71 | KMT2A (0.45) | CCNE2CCNE1CDK2AKR1C3MEN1 | |
| SCHEMBL9874612 | 0.71 | MEN1 (0.62) | MEN1KMT2ALMNANR4A1ALDH1A1 | |
| SCHEMBL12876007 | 0.71 | AXL (0.53) | CCNE2CCNE1CDK2CCNB2CDK1 | |
| SCHEMBL5001988 | 0.69 | AKR1C3 (0.44) | CCNE2CCNE1CDK2AKR1C3MEN1 | |
| SCHEMBL2212956 | 0.69 | AKR1C3 (0.48) | AKR1C3MEN1KMT2ANR4A1ALDH1A1 | |
| SCHEMBL1362487 | 0.69 | NR3C1 (0.64) | MEN1KMT2ALMNAALDH1A1MAPT | |
| SCHEMBL1124270 | 0.68 | NR1H2 (0.72) | NR1H2NR1H3MAPT | |
| SCHEMBL10498786 | 0.68 | MEN1 (0.50) | MEN1KMT2ANR1H2NR1H3MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5026711-A | Prevention and treatment of cardiovascular disorders and infections states; anxiolytic and anti-allergic agents | SANOFI (FR) | 1991-06-25 | — | — | US | disclosed |