Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNE2 | O96020 | 7/20 | 0.40 |
| ▸ | CCNE1 | P24864 | 7/20 | 0.40 |
| ▸ | CDK2 | P24941 | 7/20 | 0.40 |
| ▸ | CCNB2 | O95067 | 4/20 | 0.39 |
| ▸ | CDK1 | P06493 | 4/20 | 0.39 |
| ▸ | CCNB1 | P14635 | 4/20 | 0.39 |
| ▸ | CCNB3 | Q8WWL7 | 4/20 | 0.39 |
| ▸ | KCNQ3 | O43525 | 1/20 | 0.38 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.38 |
| ▸ | CDK7 | P50613 | 1/20 | 0.37 |
| ▸ | CCNH | P51946 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9873549 | 0.87 | CCNE2 (0.41) | CCNE2CCNE1CDK2CCNB2CDK1 | |
| SCHEMBL11717100 | 0.74 | CCNE2 (0.44) | CCNE2CCNE1CDK2CCNB2CDK1 | |
| SCHEMBL9874630 | 0.73 | KMT2A (0.50) | MEN1KMT2ANPC1CYP1A2POLB | |
| SCHEMBL9875561 | 0.72 | MEN1 (0.61) | MEN1KMT2AMAPTSMN1; SMN2NR4A1 | |
| SCHEMBL5261917 | 0.71 | CCNE2 (0.66) | CCNE2CCNE1CDK2CCNB2CDK1 | |
| SCHEMBL1915278 | 0.71 | AKR1C3 (0.47) | MEN1KMT2AAKR1C3MAPTNR4A1 | |
| SCHEMBL9875062 | 0.69 | KMT2A (0.46) | CCNE2CCNE1CDK2MEN1KMT2A | |
| SCHEMBL9874886 | 0.69 | KMT2A (0.46) | CCNE2CCNE1CDK2MEN1KMT2A | |
| SCHEMBL5001988 | 0.68 | AKR1C3 (0.44) | CCNE2CCNE1CDK2MEN1KMT2A | |
| SCHEMBL2212956 | 0.68 | AKR1C3 (0.48) | MEN1KMT2AAKR1C3MAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5026711-A | Prevention and treatment of cardiovascular disorders and infections states; anxiolytic and anti-allergic agents | SANOFI (FR) | 1991-06-25 | — | — | US | disclosed |