Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.36 |
| ▸ | CTSL | P07711 | 2/20 | 0.35 |
| ▸ | CTSB | P07858 | 2/20 | 0.35 |
| ▸ | CTSS | P25774 | 2/20 | 0.35 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.34 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.33 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.31 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.31 |
| ▸ | CTSD | P07339 | 1/20 | 0.30 |
| ▸ | AKT1 | P31749 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8737769 | 0.87 | HDAC6 (0.39) | HDAC6HDAC1HDAC2CTSLCTSB | |
| SCHEMBL28676568 | 0.80 | HDAC6 (0.36) | HDAC6HDAC1HDAC2CTSLCTSB | |
| SCHEMBL8098483 | 0.80 | HDAC6 (0.40) | HDAC6HDAC1HDAC2CTSLCTSB | |
| SCHEMBL23452708 | 0.78 | DGAT1 (0.43) | HDAC6HDAC1HDAC2DGAT1CA14 | |
| SCHEMBL3126231 | 0.78 | DGAT1 (0.38) | HDAC6HDAC1HDAC2DGAT1CA14 | |
| SCHEMBL844210 | 0.78 | HDAC6 (0.35) | HDAC6HDAC1HDAC2DGAT1CA14 | |
| SCHEMBL16998486 | 0.78 | CTSD (0.36) | HDAC6HDAC1HDAC2CTSLCTSB | |
| SCHEMBL27032752 | 0.78 | HDAC6 (0.33) | HDAC6HDAC1HDAC2DGAT1 | |
| SCHEMBL6512340 | 0.77 | HDAC6 (0.37) | HDAC6HDAC1HDAC2DGAT1CA14 | |
| SCHEMBL28652589 | 0.77 | HDAC6 (0.37) | HDAC6HDAC1HDAC2DGAT1CA14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4990508-A | Reduced side effects | TOYAMA CHEMICAL CO., LTD. (JP) | 1991-02-05 | — | — | US | disclosed |