Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | MITF | O75030 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | HTR2C | P28335 | 1/20 | 0.36 |
| ▸ | HTR2B | P41595 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1396121 | 0.81 | ALDH1A1 (0.52) | L3MBTL1ALDH1A1PKMTAAR1SMN1; SMN2 | |
| SCHEMBL19698979 | 0.80 | L3MBTL1 (0.59) | L3MBTL1ALDH1A1PKMTAAR1SMN1; SMN2 | |
| SCHEMBL21198513 | 0.78 | ALDH1A1 (0.47) | L3MBTL1ALDH1A1PKMTAAR1SMN1; SMN2 | |
| SCHEMBL2976254 | 0.77 | L3MBTL1 (0.50) | L3MBTL1ALDH1A1PKMTAAR1SMN1; SMN2 | |
| SCHEMBL16246028 | 0.77 | SMN1; SMN2 (0.64) | L3MBTL1ALDH1A1PKMTAAR1SMN1; SMN2 | |
| SCHEMBL16367359 | 0.75 | L3MBTL1 (0.43) | L3MBTL1ALDH1A1PKMTAAR1SMN1; SMN2 | |
| SCHEMBL174157 | 0.75 | ALDH1A1 (0.51) | L3MBTL1ALDH1A1PKMTAAR1SMN1; SMN2 | |
| SCHEMBL9810683 | 0.75 | L3MBTL1 (0.54) | L3MBTL1ALDH1A1PKMTAAR1SMN1; SMN2 | |
| SCHEMBL9873423 | 0.75 | ALDH1A1 (0.60) | L3MBTL1ALDH1A1PKMMAPTHTT | |
| SCHEMBL14696607 | 0.75 | L3MBTL1 (0.53) | L3MBTL1ALDH1A1PKMTAAR1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101282941-A | Imidazole compounds for the treatment of neurological disorders | PFIZER (US) | 2008-10-08 | — | — | CN | disclosed |
| US-5023361-A | Process for preparing hydroxyalkylating agents, the agents so obtained, and their use | RHONE-POULENC SANTE (FR) | 1991-06-11 | — | — | US | disclosed |
| US-4925950-A | Process for preparing 1-hydroxyalkyl-5-nitroimidazole | RHONE-POULENC SANTE (FR) | 1990-05-15 | — | — | US | disclosed |
| US-4925949-A | Process for preparing 1-alkyl-5-nitroimidazoles | RHONE-POULENC SANTE (FR) | 1990-05-15 | — | — | US | disclosed |
| US-4925951-A | Process for preparing 1-hydroxyalkyl-2-methyl-5-nitroimidazoles | RHONE-POULENC SANTE (FR) | 1990-05-15 | — | — | US | disclosed |
| US-4925952-A | Process for preparing 1-hydroxyalkyl-5-nitroimidazoles | RHONE-POULENC SANTE (FR) | 1990-05-15 | — | — | US | disclosed |