Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | HRH2 | P25021 | 10/20 | 0.51 |
| ▸ | HRH1 | P35367 | 10/20 | 0.51 |
| ▸ | THRB | P10828 | 7/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | LMNA | P02545 | 3/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.51 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.51 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.51 |
| ▸ | DRD4 | P21917 | 1/20 | 0.51 |
| ▸ | ACHE | P22303 | 1/20 | 0.51 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.51 |
| ▸ | HTR2A | P28223 | 1/20 | 0.51 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.51 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.51 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9873842 | 0.82 | PREP (0.62) | ALDH1A1MAPTKMT2A | |
| SCHEMBL9873839 | 0.82 | PREP (0.62) | ALDH1A1MAPTKMT2A | |
| SCHEMBL9874002 | 0.81 | PREP (0.49) | HRH2HRH1ALDH1A1LMNACHRM2 | |
| SCHEMBL9874007 | 0.81 | PREP (0.49) | HRH2HRH1ALDH1A1LMNACHRM2 | |
| SCHEMBL9874971 | 0.77 | L3MBTL1 (0.55) | L3MBTL1HRH2HRH1THRBALDH1A1 | |
| SCHEMBL10776986 | 0.77 | PREP (0.55) | ALDH1A1LMNAMAPTSMN1; SMN2KMT2A | |
| SCHEMBL9873491 | 0.75 | CAPN1 (0.43) | ALDH1A1LMNAHTR2AMAPTSMN1; SMN2 | |
| SCHEMBL9873469 | 0.75 | CAPN1 (0.43) | ALDH1A1LMNAHTR2AMAPTSMN1; SMN2 | |
| SCHEMBL9874715 | 0.74 | PREP (0.57) | ALDH1A1LMNASLC6A2SLC6A3HRH3 | |
| SCHEMBL9874283 | 0.74 | PREP (0.59) | ALDH1A1MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5051444-A | Pyrrolidine derivatives as anti-amnesia agents | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1991-09-24 | — | — | US | disclosed |
| US-4880827-A | Pyrrolidine derivatives having inhibitory action for proline specific endopepidase | SUMITOMO PHARMACEUTICALS COMPANY, LTD. (JP) | 1989-11-14 | — | — | US | disclosed |
| EP-0238319-A1 | Pyrrolidine derivatives | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1987-09-23 | — | — | EP | disclosed |