Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CAPN1 | P07384 | 6/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
| ▸ | HTR2C | P28335 | 1/20 | 0.41 |
| ▸ | HTR2B | P41595 | 1/20 | 0.41 |
| ▸ | GFER | P55789 | 1/20 | 0.41 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | ACE | P12821 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9873491 | 1.00 | CAPN1 (0.43) | CAPN1ALDH1A1ALOX15HTR2AHTR2C | |
| SCHEMBL9872536 | 0.77 | ALDH1A1 (0.46) | CAPN1ALDH1A1ALOX15HTR2AHTR2C | |
| SCHEMBL9874068 | 0.75 | L3MBTL1 (0.53) | ALDH1A1HTR2AMAPTLMNASMN1; SMN2 | |
| SCHEMBL9873839 | 0.75 | PREP (0.62) | ALDH1A1GFERMAPTMAPK1ACE | |
| SCHEMBL9873842 | 0.75 | PREP (0.62) | ALDH1A1GFERMAPTMAPK1ACE | |
| SCHEMBL4385546 | 0.73 | KMT2A (0.61) | ALDH1A1TSHRMEN1KMT2A | |
| SCHEMBL9875180 | 0.72 | ALDH1A1 (0.50) | ALDH1A1HSD11B1LMNASMN1; SMN2POLB | |
| SCHEMBL9875176 | 0.72 | ALDH1A1 (0.50) | ALDH1A1HSD11B1LMNASMN1; SMN2POLB | |
| Hydrochloric Acid SCHEMBL4378952 | 0.72 | KMT2A (0.60) | ALDH1A1TSHRMEN1KMT2A | |
| SCHEMBL9873608 | 0.72 | MEN1 (0.49) | ALDH1A1HSD11B1KDM4EMAPK1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5051444-A | Pyrrolidine derivatives as anti-amnesia agents | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1991-09-24 | — | — | US | disclosed |
| US-4880827-A | Pyrrolidine derivatives having inhibitory action for proline specific endopepidase | SUMITOMO PHARMACEUTICALS COMPANY, LTD. (JP) | 1989-11-14 | — | — | US | disclosed |
| EP-0238319-A1 | Pyrrolidine derivatives | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1987-09-23 | — | — | EP | disclosed |