Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RECQL | P46063 | 2/20 | 0.66 |
| ▸ | HTT | P42858 | 1/20 | 0.66 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.66 |
| ▸ | ATM | Q13315 | 1/20 | 0.57 |
| ▸ | LMNA | P02545 | 4/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | PKM | P14618 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | CYP2J2 | P51589 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9873303 | 0.94 | HTT (0.64) | RECQLHTTNPSR1CYP3A4CYP2J2 | |
| SCHEMBL9873976 | 0.84 | CYP2J2 (0.48) | RECQLHTTNPSR1ATMALDH1A1 | |
| SCHEMBL9786843 | 0.83 | BCHE (0.60) | RECQLHTTNPSR1CYP2J2 | |
| SCHEMBL9873324 | 0.81 | CYP2J2 (0.51) | RECQLHTTNPSR1CYP2J2 | |
| SCHEMBL11799658 | 0.81 | CYP2J2 (0.69) | CYP3A4CYP2J2 | |
| SCHEMBL9874149 | 0.81 | CYP2J2 (0.61) | LMNACYP3A4CYP2J2 | |
| SCHEMBL7328277 | 0.80 | GLA (0.57) | RECQLHTTNPSR1CYP2C19ALDH1A1 | |
| SCHEMBL9873355 | 0.80 | CYP2J2 (0.48) | CYP2J2 | |
| SCHEMBL9871858 | 0.80 | CYP2J2 (0.58) | LMNACYP3A4CYP2J2 | |
| Hydrochloric Acid SCHEMBL11791451 | 0.80 | CYP2J2 (0.67) | CYP3A4CYP2J2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5057524-A | Asthma, dermatitis | A. H. ROBINS COMPANY INCORPORATED (US) | 1991-10-15 | — | — | US | disclosed |