Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLA | P06280 | 1/20 | 0.57 |
| ▸ | NPY2R | P49146 | 4/20 | 0.57 |
| ▸ | HTT | P42858 | 1/20 | 0.56 |
| ▸ | RECQL | P46063 | 1/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | FAAH | O00519 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | NPC1 | O15118 | 2/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15920160 | 0.91 | HTT (0.66) | NPY2RHTTRECQLNPSR1KMT2A | |
| SCHEMBL21382028 | 0.83 | ALDH1A1 (0.63) | GLANPY2RHTTRECQLNPSR1 | |
| SCHEMBL22773254 | 0.83 | ALDH1A1 (0.63) | GLANPY2RHTTRECQLNPSR1 | |
| SCHEMBL15919999 | 0.82 | FAAH (0.61) | NPY2RHTTRECQLNPSR1KMT2A | |
| SCHEMBL22558771 | 0.81 | ALDH1A1 (0.56) | GLANPY2RKMT2AALDH1A1KDM4E | |
| SCHEMBL9872975 | 0.81 | ALDH1A1 (0.60) | NPY2RKMT2AALDH1A1KDM4E | |
| SCHEMBL9874072 | 0.80 | RECQL (0.66) | HTTRECQLNPSR1KMT2AALDH1A1 | |
| SCHEMBL15919889 | 0.80 | NPY2R (0.80) | NPY2RKMT2ASMN1; SMN2 | |
| SCHEMBL15919994 | 0.80 | NAMPT (0.55) | NPY2RHTTRECQLNPSR1KMT2A | |
| SCHEMBL15919993 | 0.80 | NPY2R (0.76) | NPY2RKMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4032642-A | SEDATIVES, TRANQUILIZERS | A. H. ROBINS COMPANY, INCORPORATED (US) | 1977-06-28 | — | — | US | claimed |
| US-3956296-A | ANTIINFLAMMATORY, SEDATIVES, TRANQUILIZERS | A. H. ROBINS COMPANY, INCORPORATED (US) | 1976-05-11 | — | — | US | claimed |