Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2J2 | P51589 | 7/20 | 0.48 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.45 |
| ▸ | HRH1 | P35367 | 1/20 | 0.45 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9873774 | 0.94 | CYP2J2 (0.56) | CYP2J2HRH1KCNH2 | |
| SCHEMBL9871849 | 0.86 | NPSR1 (0.51) | CYP2J2CYP19A1KCNH2 | |
| SCHEMBL9873976 | 0.84 | CYP2J2 (0.48) | CYP2J2 | |
| SCHEMBL9873350 | 0.84 | CYP2J2 (0.48) | CYP2J2HRH1KCNH2 | |
| SCHEMBL9256393 | 0.83 | CYP19A1 (0.49) | CYP19A1HRH1KCNH2 | |
| SCHEMBL9873524 | 0.83 | CYP2J2 (0.58) | CYP2J2HRH1KCNH2 | |
| SCHEMBL9873195 | 0.82 | CYP2J2 (0.55) | CYP2J2HRH1KCNH2 | |
| SCHEMBL9786852 | 0.82 | CYP19A1 (0.50) | CYP2J2CYP19A1HRH1KCNH2 | |
| SCHEMBL9872272 | 0.82 | CYP2J2 (0.47) | CYP2J2HRH1 | |
| SCHEMBL7321605 | 0.81 | CYP2J2 (0.72) | CYP2J2KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5057524-A | Asthma, dermatitis | A. H. ROBINS COMPANY INCORPORATED (US) | 1991-10-15 | — | — | US | disclosed |