Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | SOAT1 | P35610 | 2/20 | 0.47 |
| ▸ | FAAH | O00519 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | CNR1 | P21554 | 6/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.37 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9873770 | 0.87 | KDM4E (0.48) | KDM4ESOAT1FAAHMEN1TP53 | |
| SCHEMBL5190751 | 0.81 | ALDH1A1 (0.46) | KDM4ECYP1A2ALDH1A1POLB | |
| SCHEMBL9875348 | 0.74 | KDM4E (0.48) | KDM4ESOAT1FAAHMEN1TP53 | |
| SCHEMBL462422 | 0.70 | FAAH (0.78) | KDM4ESOAT1FAAHMEN1TP53 | |
| SCHEMBL15262896 | 0.70 | FAAH (0.78) | KDM4ESOAT1FAAHMEN1TP53 | |
| SCHEMBL2088620 | 0.70 | FAAH (0.78) | KDM4ESOAT1FAAHMEN1TP53 | |
| SCHEMBL376320 | 0.70 | FAAH (0.78) | KDM4ESOAT1FAAHMEN1TP53 | |
| SCHEMBL848425 | 0.70 | FAAH (0.78) | KDM4ESOAT1FAAHMEN1TP53 | |
| SCHEMBL15263119 | 0.70 | FAAH (0.78) | KDM4ESOAT1FAAHMEN1TP53 | |
| SCHEMBL232435 | 0.70 | FAAH (0.78) | KDM4ESOAT1FAAHMEN1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0245687-B1 | SUBSTITUTED PYRIMIDINE AMIDES OF OLEIC OR LINOLEIC ACID AS INHIBITORS OF ACYL-COA CHOLESTEROL ACYLTRANSFERASE | WARNER-LAMBERT COMPANY (US) | 1991-02-27 | — | — | EP | claimed |