Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 10/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.56 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.49 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.49 |
| ▸ | ACHE | P22303 | 2/20 | 0.49 |
| ▸ | CACNB4 | O00305 | 1/20 | 0.49 |
| ▸ | CACNA1A | O00555 | 1/20 | 0.49 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.49 |
| ▸ | CACNG3 | O60359 | 1/20 | 0.49 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.49 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.49 |
| ▸ | BCHE | P06276 | 1/20 | 0.49 |
| ▸ | CACNB3 | P54284 | 1/20 | 0.49 |
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.49 |
| ▸ | CACNG7 | P62955 | 1/20 | 0.49 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.49 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.49 |
| ▸ | CACNB1 | Q02641 | 1/20 | 0.49 |
| ▸ | CACNG1 | Q06432 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9872964 | 0.92 | MAPT (0.60) | MAPTALDH1A1MAPK1PDE4BPDE4D | |
| SCHEMBL9874545 | 0.84 | PRKCZ (0.54) | MAPTALDH1A1MAPK1CACNA1DRAB9A | |
| SCHEMBL9779333 | 0.84 | MAPT (0.61) | MAPTALDH1A1MAPK1PDE4BPDE4D | |
| SCHEMBL9779315 | 0.82 | MAPT (0.59) | MAPTALDH1A1MAPK1PDE4BPDE4D | |
| SCHEMBL2075279 | 0.82 | MAPT (0.57) | MAPTALDH1A1MAPK1PDE4BPDE4D | |
| SCHEMBL10377726 | 0.81 | ALDH1A1 (0.56) | MAPTALDH1A1MAPK1PDE4DMEN1 | |
| SCHEMBL9873424 | 0.80 | MAPT (0.56) | MAPTALDH1A1MAPK1PDE4BPDE4D | |
| SCHEMBL9779335 | 0.78 | MAPT (0.56) | MAPTALDH1A1MAPK1PDE4BPDE4D | |
| SCHEMBL9874282 | 0.78 | MAPT (0.55) | MAPTALDH1A1PDE4BPDE4DRAB9A | |
| Hydrochloric Acid SCHEMBL10376597 | 0.78 | MAPT (0.55) | MAPTALDH1A1MAPK1PDE4BPDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4990507-A | Cardiotonic agents | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1991-02-05 | — | — | US | disclosed |
| EP-0228845-B1 | N-CONTAINING HETEROCYCLIC COMPOUNDS, PROCESSES FOR THE PREPARATION THEREOF AND COMPOSITION COMPRISING THE SAME | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1990-12-12 | — | — | EP | disclosed |
| US-4931453-A | CARDIOVASCULAR, HYPOTENSIVE AGENTS | FUJISAWA PHARMACEUTICAL COMPANY, LTD. (JP) | 1990-06-05 | — | — | US | disclosed |
| US-4857527-A | HYPOTENSIVE, ANTISCHEMIC AGENT | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1989-08-15 | — | — | US | disclosed |
| US-4831030-A | FOR CEREBROVASCULAR DISEASES; HYPERTENSIVE AGENTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1989-05-16 | — | — | US | disclosed |
| EP-0228845-A2 | N-containing heterocyclic compounds, processes for the preparation thereof and composition comprising the same | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1987-07-15 | — | — | EP | disclosed |