Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMO | O15229 | 1/20 | 0.52 |
| ▸ | NOS1 | P29475 | 4/20 | 0.44 |
| ▸ | NOS3 | P29474 | 3/20 | 0.44 |
| ▸ | NOS2 | P35228 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | THPO | P40225 | 1/20 | 0.44 |
| ▸ | BLM | P54132 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | OGT | O15294 | 1/20 | 0.41 |
| ▸ | PDE3B | Q13370 | 2/20 | 0.39 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.39 |
| ▸ | ACLY | P53396 | 1/20 | 0.38 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | PPM1D | O15297 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7067142 | 0.93 | KMO (0.52) | KMONOS1NOS3NOS2LMNA | |
| SCHEMBL9680309 | 0.84 | KMO (0.59) | KMONOS1NOS3NOS2LMNA | |
| SCHEMBL2549381 | 0.84 | KMO (0.59) | KMONOS1NOS3NOS2LMNA | |
| SCHEMBL11040016 | 0.78 | NOS1 (0.53) | KMONOS1NOS3NOS2LMNA | |
| SCHEMBL11045421 | 0.78 | KMO (0.72) | KMONOS1NOS3NOS2LMNA | |
| SCHEMBL24981075 | 0.78 | KMO (0.52) | KMONOS1NOS3NOS2LMNA | |
| SCHEMBL5536562 | 0.78 | NOS1 (0.53) | KMONOS1NOS3NOS2LMNA | |
| SCHEMBL31180320 | 0.78 | KMO (0.52) | KMONOS1NOS3NOS2LMNA | |
| SCHEMBL29455648 | 0.78 | KMO (0.52) | KMONOS1NOS3NOS2LMNA | |
| SCHEMBL782747 | 0.78 | KMO (0.52) | KMONOS1NOS3NOS2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5007952-A | Herbicidal novel benzothiazolonyl pyrroles | NIHON TOKUSHU NOYAKU SEIZO K.K. (JP) | 1991-04-16 | — | — | US | disclosed |
| EP-0369262-A2 | Novel pyrroles | NIHON BAYER AGROCHEM K.K. (JP) | 1990-05-23 | — | — | EP | disclosed |