Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 6/20 | 0.44 |
| ▸ | RAB9A | P51151 | 4/20 | 0.44 |
| ▸ | NPC1 | O15118 | 3/20 | 0.44 |
| ▸ | HTT | P42858 | 3/20 | 0.44 |
| ▸ | AR | P10275 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | PKM | P14618 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 4/20 | 0.39 |
| ▸ | PDE3B | Q13370 | 2/20 | 0.37 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9389636 | 0.85 | RXFP1 (0.45) | RXFP1MAPTRAB9ANPC1HTT | |
| SCHEMBL9874038 | 0.83 | MAPT (0.44) | RXFP1MAPTRAB9ANPC1HTT | |
| SCHEMBL31490586 | 0.79 | RXFP1 (0.44) | RXFP1MAPTRAB9ANPC1HTT | |
| SCHEMBL340529 | 0.72 | RXFP1 (0.47) | RXFP1MAPTRAB9ANPC1SMN1; SMN2 | |
| SCHEMBL9874930 | 0.71 | MAPT (0.48) | RXFP1MAPTRAB9ANPC1HTT | |
| SCHEMBL31490598 | 0.71 | PDE3B (0.41) | RXFP1MAPTPDE3BPDE3A | |
| SCHEMBL6987665 | 0.71 | RAB9A (0.40) | RXFP1MAPTRAB9ANPC1HTT | |
| SCHEMBL12206691 | 0.70 | MAPT (0.84) | RXFP1MAPTRAB9ANPC1HTT | |
| SCHEMBL31490607 | 0.70 | TP53 (0.47) | MAPTSMN1; SMN2TP53THRBMAOB | |
| SCHEMBL9390809 | 0.68 | RXFP1 (0.55) | RXFP1MAPTRAB9ANPC1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5017576-A | Antianxiolytic, hypnotic, anticonvulsant, antiepileptic | RHONE-POULENC SANTE (FR) | 1991-05-21 | — | — | US | disclosed |