Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 4/20 | 0.57 |
| ▸ | RAB9A | P51151 | 4/20 | 0.57 |
| ▸ | MEN1 | O00255 | 2/20 | 0.56 |
| ▸ | LMNA | P02545 | 2/20 | 0.56 |
| ▸ | MAPT | P10636 | 2/20 | 0.56 |
| ▸ | HTT | P42858 | 2/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | KCNK3 | O14649 | 2/20 | 0.54 |
| ▸ | KCNK9 | Q9NPC2 | 2/20 | 0.54 |
| ▸ | IDO1 | P14902 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.49 |
| ▸ | HTR3B | O95264 | 1/20 | 0.49 |
| ▸ | HTR3A | P46098 | 1/20 | 0.49 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.49 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1437377 | 0.91 | NPC1 (0.65) | NPC1RAB9AMEN1LMNAMAPT | |
| SCHEMBL2287569 | 0.80 | MEN1 (0.64) | NPC1RAB9AMEN1LMNAMAPT | |
| SCHEMBL641112 | 0.79 | PARP1 (0.48) | NPC1RAB9AMEN1HTTKMT2A | |
| Hydrochloric Acid SCHEMBL15527640 | 0.79 | MEN1 (0.62) | NPC1RAB9AMEN1LMNAMAPT | |
| SCHEMBL3675463 | 0.78 | KCNK3 (0.84) | NPC1RAB9AMEN1LMNAMAPT | |
| SCHEMBL10974846 | 0.78 | IDO1 (0.59) | NPC1RAB9AMEN1LMNAMAPT | |
| SCHEMBL1437533 | 0.77 | FADS1 (0.53) | NPC1RAB9AMEN1LMNAMAPT | |
| SCHEMBL2952721 | 0.77 | PARP1 (0.52) | NPC1RAB9AMEN1HTTKMT2A | |
| SCHEMBL4093723 | 0.77 | MEN1 (0.60) | NPC1RAB9AMEN1LMNAMAPT | |
| SCHEMBL13584733 | 0.77 | MEN1 (0.60) | NPC1RAB9AMEN1LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5026711-A | Prevention and treatment of cardiovascular disorders and infections states; anxiolytic and anti-allergic agents | SANOFI (FR) | 1991-06-25 | — | — | US | disclosed |