Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | MTOR | P42345 | 1/20 | 0.47 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.42 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.42 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.40 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.39 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | CDC7 | O00311 | 1/20 | 0.38 |
| ▸ | KIF11 | P52732 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | CTSV | O60911 | 1/20 | 0.37 |
| ▸ | CTSL | P07711 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9873449 | 0.87 | HPGD (0.50) | NPC1MTORFFAR1TRPA1LMNA | |
| SCHEMBL9872630 | 0.80 | CTSV (0.57) | LMNAHPGDKDM4EMEN1ALDH1A1 | |
| SCHEMBL9874829 | 0.78 | HPGD (0.60) | CSNK1DLMNAHPGDCDC7KDM4E | |
| SCHEMBL9872701 | 0.77 | HPGD (0.43) | LMNAHPGDKDM4EMEN1ALDH1A1 | |
| SCHEMBL9872054 | 0.76 | HPGD (0.56) | NPC1LMNAHPGDKDM4EMEN1 | |
| SCHEMBL9872034 | 0.76 | KMT2A (0.56) | NPC1LMNAHPGDKDM4EMEN1 | |
| SCHEMBL339070 | 0.75 | CTSV (0.62) | NPC1MTORADORA2AADORA1LMNA | |
| SCHEMBL29411907 | 0.75 | CTSV (0.62) | NPC1MTORADORA2AADORA1LMNA | |
| SCHEMBL339993 | 0.74 | NPC1 (0.48) | NPC1MTORADORA2AADORA1FFAR1 | |
| SCHEMBL19032114 | 0.74 | MAPT (0.49) | LMNAHPGDKIF11KDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5017576-A | Antianxiolytic, hypnotic, anticonvulsant, antiepileptic | RHONE-POULENC SANTE (FR) | 1991-05-21 | — | — | US | disclosed |