Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 5/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | AHR | P35869 | 1/20 | 0.41 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.40 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | CTSV | O60911 | 2/20 | 0.39 |
| ▸ | CTSL | P07711 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | PARP1 | P09874 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9874829 | 0.85 | HPGD (0.60) | HPGDALDH1A1LMNAKDM4EMAPT | |
| SCHEMBL9872054 | 0.85 | HPGD (0.56) | HPGDALDH1A1LMNAKDM4EMAPT | |
| SCHEMBL9872630 | 0.83 | CTSV (0.57) | HPGDALDH1A1LMNAKDM4EMAPT | |
| SCHEMBL9872034 | 0.80 | KMT2A (0.56) | HPGDALDH1A1LMNAKDM4EMAPT | |
| SCHEMBL9874994 | 0.79 | KDM4E (0.59) | HPGDALDH1A1LMNAKDM4EMAPT | |
| SCHEMBL9874866 | 0.77 | NPC1 (0.47) | HPGDALDH1A1LMNAKDM4EMEN1 | |
| SCHEMBL19032114 | 0.76 | MAPT (0.49) | HPGDALDH1A1LMNAKDM4EMAPT | |
| SCHEMBL9872570 | 0.76 | CYP19A1 (0.46) | HPGDALDH1A1LMNAKDM4EMAPT | |
| SCHEMBL9873449 | 0.75 | HPGD (0.50) | HPGDALDH1A1LMNAKDM4EPDE3B | |
| SCHEMBL9874926 | 0.72 | HPGD (0.60) | HPGDALDH1A1LMNAKDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5017576-A | Antianxiolytic, hypnotic, anticonvulsant, antiepileptic | RHONE-POULENC SANTE (FR) | 1991-05-21 | — | — | US | disclosed |