Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 3/20 | 0.55 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | FEN1 | P39748 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | DHODH | Q02127 | 1/20 | 0.41 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.41 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.41 |
| ▸ | COMT | P21964 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | KDR | P35968 | 1/20 | 0.40 |
| ▸ | METAP2 | P50579 | 1/20 | 0.40 |
| ▸ | METAP1 | P53582 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9874891 | 0.84 | HTT (0.54) | HTTMAPTGAANPSR1KMT2A | |
| SCHEMBL21730579 | 0.75 | ALDH1A1 (0.50) | MAPTNPSR1KDM4ETP53HSD17B10 | |
| SCHEMBL13943539 | 0.75 | PRMT5 (0.46) | HTTMAPTGAAKMT2AMEN1 | |
| SCHEMBL9872674 | 0.74 | ALDH1A1 (0.45) | HTTMAPTNPSR1KMT2AMEN1 | |
| SCHEMBL20659711 | 0.73 | PDE10A (0.61) | HTTMAPTNPSR1KMT2AMEN1 | |
| SCHEMBL29810209 | 0.72 | ALDH1A1 (0.46) | HTTMAPTKMT2AMEN1KDM4E | |
| SCHEMBL29810203 | 0.72 | ALDH1A1 (0.46) | HTTKMT2AMEN1KDM4ETP53 | |
| Benzophenone SCHEMBL29065284 | 0.70 | ALDH1A1 (0.61) | HTTMAPTKMT2AMEN1KDM4E | |
| SCHEMBL20669628 | 0.70 | PDE10A (0.45) | HTTMAPTGAANPSR1KMT2A | |
| SCHEMBL21939918 | 0.70 | PDE10A (0.49) | HTTMAPTNPSR1KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5026711-A | Prevention and treatment of cardiovascular disorders and infections states; anxiolytic and anti-allergic agents | SANOFI (FR) | 1991-06-25 | — | — | US | disclosed |