Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 3/20 | 0.54 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | DHODH | Q02127 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | KDR | P35968 | 1/20 | 0.39 |
| ▸ | METAP2 | P50579 | 1/20 | 0.39 |
| ▸ | METAP1 | P53582 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
| ▸ | FABP3 | P05413 | 1/20 | 0.39 |
| ▸ | FABP4 | P15090 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9874905 | 0.84 | HTT (0.55) | HTTMAPTGAANPSR1KMT2A | |
| SCHEMBL9381144 | 0.75 | HTT (0.40) | HTTMAPTGAANPSR1KMT2A | |
| SCHEMBL29108495 | 0.75 | LMNA (0.46) | MAPTKDM4EHSD17B10DHODHALDH1A1 | |
| SCHEMBL30640157 | 0.75 | LMNA (0.46) | MAPTKDM4EHSD17B10DHODHALDH1A1 | |
| SCHEMBL9873674 | 0.74 | KMT2A (0.42) | HTTMAPTNPSR1KMT2AMEN1 | |
| SCHEMBL12564559 | 0.74 | PABPC1 (0.44) | MAPTKMT2AMEN1KDM4ETP53 | |
| SCHEMBL20659711 | 0.72 | PDE10A (0.61) | HTTMAPTNPSR1KMT2AMEN1 | |
| SCHEMBL20669725 | 0.71 | PDE10A (0.47) | HTTMAPTNPSR1KDM4ETP53 | |
| SCHEMBL1991038 | 0.70 | KDM4E (0.43) | HTTMAPTGAANPSR1KMT2A | |
| SCHEMBL30640208 | 0.70 | KDM4E (0.43) | HTTMAPTGAANPSR1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5026711-A | Prevention and treatment of cardiovascular disorders and infections states; anxiolytic and anti-allergic agents | SANOFI (FR) | 1991-06-25 | — | — | US | disclosed |